Boc-Asp(OtBu)-O-(NHS)
Boc-Asp(OtBu)-O-(NHS), identified by CAS number 72671-27-3 and with the molecular formula C17H26N2O8, is a protected amino acid derivative. Its molecular weight is 386.40 g/mol. This compound serves as a valuable building block in peptide synthesis and related organic chemistry applications, facilitating the controlled formation of peptide bonds. It is typically stored at "-20°C" to maintain its integrity.
- IUPAC
- Boc-L-aspartic acid 4-(tert-butyl) 1-(hydroxysuccinimide) ester

Peptide Synthesis
This activated ester is widely employed in solid-phase and solution-phase peptide synthesis. The N-terminal Boc protection and the tert-butyl ester protection on the side chain allow for selective deprotection strategies during peptide chain elongation.
Organic Synthesis
Beyond peptide chemistry, Boc-Asp(OtBu)-O-(NHS) finds utility in general organic synthesis where an aspartic acid residue needs to be incorporated into a molecule. Its activated ester functionality enables coupling reactions with various nucleophiles.
Bioconjugation
The N-hydroxysuccinimide ester moiety is reactive towards primary amines, making this compound suitable for labelling or conjugating aspartic acid residues to proteins, peptides, or other biomolecules.
| Molecular weight | 386.40 |
|---|---|
| Empirical formula | C17H26N2O8 |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Asp(OtBu)-O-(NHS) used for?
+
Boc-Asp(OtBu)-O-(NHS) is primarily used as a protected amino acid building block in peptide synthesis and other organic chemistry applications requiring the controlled incorporation of an aspartic acid residue.
What are the CAS number and molecular formula for Boc-Asp(OtBu)-O-(NHS)?
+
The CAS number for Boc-Asp(OtBu)-O-(NHS) is 72671-27-3, and its molecular formula is C17H26N2O8.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Boc-Asp(OtBu)-O-(NHS) for research and laboratory use. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should Boc-Asp(OtBu)-O-(NHS) be handled and stored?
+
According to the supplied safety data, Boc-Asp(OtBu)-O-(NHS) has a WGK Germany rating of 3, indicating it is hazardous to water. It should be stored at -20°C. Handle with appropriate personal protective equipment in a well-ventilated area.
Is Boc-Asp(OtBu)-O-(NHS) a controlled substance?
+
The provided data does not indicate that Boc-Asp(OtBu)-O-(NHS) is a controlled substance.
How can I request a quote or sample?
+
To request a quote or sample, please contact our sales department via the website or directly through the provided contact information, specifying the product name and CAS number.
How is this chemical packed and exported?
+
Tech Serve Solutions packages and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant shipping and customs regulations for hazardous materials.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis