BIS-TRIS hydrochloride

CAS 124763-51-5C8H19NO5 · HClBiochemicals & Reagents

BIS-TRIS hydrochloride (CAS: 124763-51-5), a zwitterionic organic chemical compound with the formula C8H19NO5 · HCl, has a molecular weight of 245.70. It is a valuable biological buffer that functions effectively within the useful pH range of 5.8 to 7.2, with a pKa of 6.5. BIS-TRIS hydrochloride is primarily utilised in diagnostic assay manufacturing and various biochemical research applications requiring precise pH control.

IUPAC: 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol,2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol,Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane
Synonyms: 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol hydrochloride, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride, Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane hydrochloride

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BIS-TRIS hydrochloride (C8H19NO5 · HCl) — chemical structure, CAS 124763-51-5; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsBiological BuffersBuffers / Buffer saltsBuffers A to ZCore BioreagentsGood’s BuffersResearch Essentials More...

01 /Applications

Diagnostic Assay Manufacturing

BIS-TRIS hydrochloride serves as a crucial buffer in the development and production of diagnostic assays, ensuring stable pH conditions for enzymatic reactions and other biochemical processes critical to test accuracy.

Biochemical Research

This compound is employed as a biological buffer in a wide array of life science research applications, including DNA/RNA electrophoresis and other molecular biology techniques where maintaining a specific pH is essential for experimental integrity.

Buffer Solutions

As a component of Good's buffers, BIS-TRIS hydrochloride contributes to the formulation of stable and reliable buffer solutions for sensitive biological and chemical experiments, supporting a pH range suitable for many biological systems.

02 /Properties

Molecular weight	245.70
Empirical formula	C8H19NO5 · HCl
Assay	≥99.0% (titration)

03 /Identifiers & registry

CAS number

124763-51-5

MDL number

MFCD00171252

PubChem substance

24891891

04 /Additional specifications

Pka	6.5
Market Segment	Diagnostic Assay Manufacturing
Useful Ph Range	5.8 - 7.2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is BIS-TRIS hydrochloride used for?

BIS-TRIS hydrochloride is primarily used in diagnostic assay manufacturing and various biochemical research applications, particularly where precise pH control is required within the range of 5.8 to 7.2.

What are the CAS number and formula for BIS-TRIS hydrochloride?

The CAS number for BIS-TRIS hydrochloride is 124763-51-5, and its empirical formula is C8H19NO5 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies BIS-TRIS hydrochloride with an assay of ≥99.0% (titration). We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.

What are the safety and handling recommendations for BIS-TRIS hydrochloride?

BIS-TRIS hydrochloride is classified under WGK Germany 3, indicating it is hazardous to water. Appropriate safety precautions should be taken during handling to prevent environmental release and exposure. Please refer to the Safety Data Sheet for comprehensive guidance.

How is BIS-TRIS hydrochloride packed, shipped, and exported?

Tech Serve Solutions ensures that BIS-TRIS hydrochloride is appropriately packed and prepared for secure shipment and export, adhering to all relevant regulations for chemical transport.

How can I request a sample or a quote for BIS-TRIS hydrochloride?

To request a sample or a quote for BIS-TRIS hydrochloride, please contact our sales team through the details provided on the Tech Serve Solutions website.