Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride (CAS: 68641-49-6; Formula: C6H8ClN2O5P) is a chemical compound with a molecular weight of 254.56. It functions as an effective reagent for activating carboxyl groups and is particularly useful in peptide coupling reactions within organic synthesis. Tech Serve Solutions supplies this compound, ensuring adherence to high standards for research and industrial applications.
- IUPAC
- BOP-Cl,Phosphoric acid bis(2-oxooxazolidide) chloride
Carboxyl Group Activation
This compound serves as a valuable reagent for activating carboxylic acid functionalities. This activation is a critical step in various synthetic transformations, enabling further reactions with nucleophiles.
Peptide Synthesis
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride is employed as a coupling reagent in peptide synthesis. It facilitates the formation of amide bonds between amino acids, a fundamental process in constructing peptide chains.
Heterocyclic Chemistry
As a building block containing oxazolidine rings, it can be utilised in the synthesis of more complex heterocyclic structures, contributing to the diversity of organic molecules.
| Molecular weight | 254.56 |
|---|---|
| Empirical formula | C6H8ClN2O5P |
| Assay | 97% |
| Application | Reagent for activating carboxyl groups and coupling peptides. |
| Melting point | 191 °C (dec.)(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2-oxo-3-oxazolidinyl)phosphinic chloride used for?
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Bis(2-oxo-3-oxazolidinyl)phosphinic chloride is primarily used as a reagent for activating carboxyl groups and for coupling peptides in chemical synthesis.
What are the CAS number and formula for Bis(2-oxo-3-oxazolidinyl)phosphinic chloride?
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The CAS number is 68641-49-6 and the empirical formula (Hill notation) is C6H8ClN2O5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(2-oxo-3-oxazolidinyl)phosphinic chloride with a minimum purity of 97%. This product is suitable for research and chemical synthesis applications and is not represented as USP, BP, or EP grade.
How should Bis(2-oxo-3-oxazolidinyl)phosphinic chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (type N100 US or P3 EN143 filters), is essential. Handle with extreme caution in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
Is this chemical controlled or scheduled?
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The provided data does not indicate that Bis(2-oxo-3-oxazolidinyl)phosphinic chloride is a controlled or scheduled substance. However, users should always verify local regulations.
How is Bis(2-oxo-3-oxazolidinyl)phosphinic chloride packed and shipped?
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This chemical is typically packed in accordance with UN 3261, 8/PGII regulations for transport. As a global supplier and exporter, TSS ensures compliant packaging and shipping procedures for international delivery.
How can I request a quote or sample?
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To request a quote or sample of Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, please use the contact form on our website or call our sales department. Specify the quantity required for your quotation or sample request.
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