Ammonium trifluoroacetate
Ammonium trifluoroacetate (CAS: 3336-58-1, CF3CO2NH4) is a versatile chemical compound with a molecular weight of 131.05 g/mol. It is primarily utilised as a reagent in mass spectrometry and for various applications in chemical synthesis. Its properties also lend themselves to use in analytical chemistry and spectroscopy, making it a valuable component in laboratory settings for research and development.
- IUPAC
- Trifluoroacetic acid ammonium salt

Mass Spectrometry Reagent
Ammonium trifluoroacetate is specifically graded for use in mass spectrometry, serving as an effective mobile phase additive. It aids in ionisation and improves the detection of analytes.
Chemical Synthesis
This compound functions as a reagent in various organic synthesis pathways. Its trifluoroacetate moiety can be incorporated into target molecules or act as a catalyst or source of fluoride.
Analytical Chemistry
Ammonium trifluoroacetate is employed in analytical procedures due to its distinct chemical properties. It can be used as a standard or a component in chromatographic separations.
Spectroscopy
The compound finds application in spectroscopic analyses, where its predictable behaviour and spectral characteristics are beneficial for calibration and as a reference material.
| Molecular weight | 131.05 |
|---|---|
| Linear formula | CF3CO2NH4 |
| Assay | 98% |
| Grade | for mass spectrometry |
| Melting point | 123-125 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| λ | 10 % in H2O (20°C)λ: 280 nm Amax: ≤0.03 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ammonium trifluoroacetate used for?
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Ammonium trifluoroacetate is primarily used as a reagent in mass spectrometry, for chemical synthesis, and in analytical chemistry and spectroscopy.
What is the CAS number and chemical formula for Ammonium trifluoroacetate?
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The CAS number for Ammonium trifluoroacetate is 3336-58-1, and its chemical formula is CF3CO2NH4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ammonium trifluoroacetate in a 'for mass spectrometry' grade with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
How should Ammonium trifluoroacetate be handled safely?
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Ammonium trifluoroacetate is a warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is Ammonium trifluoroacetate a controlled substance?
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The provided data does not indicate that Ammonium trifluoroacetate is a controlled substance.
How is Ammonium trifluoroacetate packed, shipped, or exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packaging and compliance for shipping and exporting Ammonium trifluoroacetate worldwide.
How can I request a quote or sample for Ammonium trifluoroacetate?
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To request a quote or sample for Ammonium trifluoroacetate, please contact the Tech Serve Solutions sales team through our official channels.
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