Benzyl bromoacetate
Benzyl bromoacetate (CAS 5437-45-6) is an organic ester with the linear formula BrCH2COOCH2C6H5 and a molecular weight of 229.07 g/mol. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and development for alkylation reactions, contributing to the creation of more complex molecules within pharmaceutical and fine chemical sectors.
- IUPAC
- Bromoacetic acid benzyl ester
Organic Synthesis Intermediate
Benzyl bromoacetate functions as an alkylating agent in various organic synthesis pathways. Its reactivity allows for the introduction of the bromoacetyl moiety into other molecules, facilitating the construction of diverse chemical structures.
Pharmaceutical Research
This compound has been employed in the synthesis of pharmaceutical intermediates. For instance, it was used in the alkylation of specific carbohydrates to produce complex lipopeptides, showcasing its utility in medicinal chemistry research.
Fine Chemical Production
As a versatile building block, Benzyl bromoacetate finds application in the broader fine chemical industry. It enables the preparation of specialised organic compounds for various downstream applications.
| Molecular weight | 229.07 |
|---|---|
| Linear formula | BrCH2COOCH2C6H5 |
| Assay | 96% |
| Boiling point | 166-170 °C/22 mmHg(lit.) |
| Density | 1.446 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.544(lit.) |
| Application | Benzyl bromoacetate was used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzyl bromoacetate used for?
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Benzyl bromoacetate is primarily used as a building block and alkylating agent in organic synthesis, particularly in pharmaceutical research and fine chemical production for creating complex molecules.
What is the CAS number and molecular formula for Benzyl bromoacetate?
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The CAS number for Benzyl bromoacetate is 5437-45-6, and its linear formula is BrCH2COOCH2C6H5.
What grade and purity does Tech Serve Solutions supply for Benzyl bromoacetate?
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Tech Serve Solutions supplies Benzyl bromoacetate with a minimum assay of 96%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should Benzyl bromoacetate be handled safely?
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Benzyl bromoacetate is a skin, eye, and respiratory irritant (H315, H319, H335). Safe handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, along with good ventilation. Always consult the Safety Data Sheet before use.
Does TSS export Benzyl bromoacetate?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Benzyl bromoacetate, serving customers worldwide.
How can I request a quote or sample of Benzyl bromoacetate?
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To request a quote or a sample of Benzyl bromoacetate, please contact our sales team through the website or by phone, providing your specific requirements.
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