Benzyl chloride
Benzyl chloride (CAS: 100-44-7), with the molecular formula C6H5CH2Cl and a molecular weight of 126.58 g/mol, is a colourless to pale yellow liquid. It serves as a crucial intermediate in organic synthesis, particularly in the production of benzyl derivatives, pharmaceuticals, and fragrances. Its reactive nature makes it valuable for introducing the benzyl group into various organic molecules.
- IUPAC
- α-Chlorotoluene
- Synonyms
- α-Chlorotoluene
Pharmaceutical Synthesis
Benzyl chloride is employed as a key building block in the synthesis of various pharmaceutical compounds. It is used to introduce benzyl protecting groups or to form critical benzyl ether and ester linkages within drug molecules.
Agrochemical Production
It acts as an intermediate in the manufacturing of certain pesticides and herbicides. The benzyl moiety is incorporated into active ingredients to impart specific biological activities.
Fragrance and Flavour Industry
Benzyl chloride is a precursor for synthesising various benzyl esters and ethers, which are widely used as fragrance and flavour components in perfumes, cosmetics, and food products.
Dye and Pigment Manufacturing
It finds application in the production of certain dyes and pigments, where the benzyl group contributes to the chromophoric system or influences solubility and stability.
Polymer Additives
Benzyl chloride can be used in the synthesis of specialty chemicals that function as plasticizers or other additives in polymer formulations.
| Molecular weight | 126.58 |
|---|---|
| Linear formula | C6H5CH2Cl |
| Assay | ≥99.0% (GC) |
| Grade | purum |
| Boiling point | 177-181 °C(lit.) |
| Density | 1.1 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.538(lit.)n20/D 1.539 |
| Melting point | −43 °C(lit.) |
| Vapour pressure | 10.3 mmHg (60 °C)7 mmHg (55 °C) |
| Vapour density | 4.36 (vs air) |
| Autoignition temp | 1085 °F |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H331Toxic if inhaled
- H335May cause respiratory irritation
- H350May cause cancer
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1738 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-22-23-37/38-41-48/22 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 14 % |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzyl chloride primarily used for?
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Benzyl chloride is primarily used as an intermediate in organic synthesis for the production of pharmaceuticals, agrochemicals, fragrances, dyes, and other specialty chemicals.
What are the CAS number and molecular formula for Benzyl chloride?
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The CAS number for Benzyl chloride is 100-44-7, and its molecular formula is C6H5CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzyl chloride with a purity of ≥99.0% (GC) and a 'purum' grade. We do not represent this product as USP, BP, or EP grade.
How should Benzyl chloride be handled safely?
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Benzyl chloride is a dangerous substance requiring careful handling. It is classified as corrosive and toxic, causing severe skin burns and eye damage, and is harmful if inhaled or swallowed. Always wear appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles and face shield), and respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling guidelines.
Is Benzyl chloride a controlled substance?
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Based on the provided data, Benzyl chloride is not explicitly listed as a controlled or scheduled substance. However, its hazardous properties necessitate adherence to all relevant chemical handling regulations.
How is Benzyl chloride packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports Benzyl chloride in compliance with international transport regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or sample of Benzyl chloride?
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To request a quote or a sample of Benzyl chloride, please contact our sales department via the website or your dedicated account manager, providing your contact details and the quantity required.
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