AMD3100 octahydrochloride hydrate

CAS 155148-31-5 (anhydrous)C28H54N8 · 8HCl · xH2OCell Biology

AMD3100 octahydrochloride hydrate (CAS: 155148-31-5) is a chemical compound with the formula C28H54N8 · 8HCl · xH2O and a molecular weight of 794.47 g/mol on an anhydrous basis. It functions as a highly specific antagonist for the chemokine receptor CXCR4. This property makes it valuable in biological research, particularly in studies involving cell signaling, stem cell biology, and the investigation of chemokine-mediated processes. Its applications extend to cell biology and neuroscience research.

IUPAC: 1,1′-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride,JM3100,Plerixafor,SID791
Synonyms: 1,1′-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride,JM3100,Plerixafor,SID791

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AMD3100 octahydrochloride hydrate (C28H54N8 · 8HCl · xH2O) — chemical structure, CAS 155148-31-5 (anhydrous); Life Science, fine chemical supplied by Tech Serve Solutions

Bioactives/SupplementsCell BiologyChemokine InhibitorsChemokinesCytokines and Growth FactorsCytokinesGrowth Factors and HormonesGeneral Stem Cell BiologySanofi AventisStem Cell Biology

01 /Applications

CXCR4 Antagonist

AMD3100 is a selective antagonist of the CXCR4 chemokine receptor. It has been utilised in research to block CXCR4 signalling pathways, which are implicated in various cellular processes and disease states.

Cell Biology Research

This compound serves as a tool in cell biology studies, particularly those focusing on cell migration, immune responses, and stem cell mobilisation, where CXCR4 plays a critical role.

Drug Candidate Research

As an approved therapeutic/drug candidate, AMD3100 is investigated for its potential in various therapeutic areas. Its role in blocking CXCR4 has been explored in contexts such as cancer metastasis.

02 /Properties

Molecular weight	794.47 (anhydrous basis)
Empirical formula	C28H54N8 · 8HCl · xH2O
Assay	≥97% (NMR)
Form	solid
Solubility	H2O: ≥10 mg/mL, clear
Storage temperature	−20°C
Application	AMD3100 is a highly specific chemokine receptor CXCR4 antagonist. AMD3100 has been used in a study to determine the blockade of CXCR4 in oral squamous cell carcinoma and inhibition of lymph node metastases.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

155148-31-5 (anhydrous)

PubChem substance

24724394

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is AMD3100 octahydrochloride hydrate used for?

AMD3100 octahydrochloride hydrate is used as a highly specific CXCR4 antagonist in research. It is applied in cell biology, cell signaling, neuroscience, and stem cell research, and is considered an approved therapeutic/drug candidate.

What is the CAS number and formula for AMD3100 octahydrochloride hydrate?

The CAS number for the anhydrous form is 155148-31-5. The empirical formula is C28H54N8 · 8HCl · xH2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies AMD3100 octahydrochloride hydrate with a purity of ≥97% (NMR). We do not represent this product as USP, BP, or EP grade.

How should AMD3100 octahydrochloride hydrate be handled?

When handling AMD3100 octahydrochloride hydrate, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3.

How is AMD3100 octahydrochloride hydrate shipped and exported?

As a specialist global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping procedures for AMD3100 octahydrochloride hydrate, adhering to all relevant regulations for international export.

How can I request a sample or quote for AMD3100 octahydrochloride hydrate?

To request a sample or obtain a quote for AMD3100 octahydrochloride hydrate, please contact our sales department through the details provided on our website.