AM281
AM281 (CAS: 202463-68-1), with the molecular formula C21H19Cl2IN4O2 and a molecular weight of 557.21, is a research chemical supplied by Tech Serve Solutions. This compound is primarily utilised as a bioactive small molecule in research settings, particularly within the fields of cell biology, cell signaling, neuroscience, and neurobiology. Its known applications involve acting as a cannabinoid receptor antagonist, aiding in the study of these critical biological pathways.
- IUPAC
- 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide,AM 281
Cannabinoid Receptor Research
AM281 serves as a selective antagonist for the cannabinoid receptor 1 (CB1). This makes it a valuable tool for researchers investigating the endocannabinoid system's role in various physiological and pathological processes.
Neuroscience and Neurobiology Studies
Its antagonist properties enable detailed exploration of neurobiological functions influenced by cannabinoid signaling. Researchers use AM281 to elucidate pathways involved in learning, memory, pain perception, and mood regulation.
Cell Signaling Investigations
As a tool compound, AM281 assists in dissecting complex cell signaling cascades that are modulated by CB1 activation. This helps in understanding cellular responses in different biological contexts.
Pharmacological Research
AM281 is employed in pharmacological studies to understand the effects of CB1 receptor blockade. This can aid in the development of therapeutic strategies targeting conditions influenced by this receptor system.
| Molecular weight | 557.21 |
|---|---|
| Empirical formula | C21H19Cl2IN4O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >6 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Cnr1(25248) |
|---|---|
| Storage Condition | desiccatedunder inert gas |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is AM281 primarily used for?
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AM281 is primarily used as a selective antagonist for the cannabinoid receptor 1 (CB1) in research settings, particularly in neuroscience, neurobiology, cell biology, and cell signaling studies.
What are the CAS number and molecular formula for AM281?
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The CAS number for AM281 is 202463-68-1, and its molecular formula is C21H19Cl2IN4O2.
What grade and purity does Tech Serve Solutions supply for AM281?
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Tech Serve Solutions supplies AM281 with an assay of ≥98% (HPLC). We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should AM281 be handled safely?
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AM281 is classified as Danger with hazards including acute toxicity (oral) and skin/eye irritation. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Handle in a well-ventilated area and avoid dust formation.
Is AM281 a controlled substance?
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The provided data does not indicate that AM281 is a controlled substance.
How is AM281 shipped and exported?
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AM281 is shipped as a white powder and is subject to international regulations for hazardous materials (UN 2811, 6.1/PGIII). Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all necessary compliance.
How can I request a sample or quote for AM281?
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To request a sample or a quote for AM281, please contact our sales department through the website or by phone, providing the product name and CAS number (202463-68-1).
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