Benzamil hydrochloride hydrate
Benzamil hydrochloride hydrate (CAS: 161804-20-2) is a yellow crystalline solid with the molecular formula C13H14ClN7O · HCl · xH2O. As a potent modulator of voltage-gated sodium channels, it is a valuable research tool in cell biology and neuroscience. Its primary applications lie in investigating ion channel function, particularly within cellular signaling pathways. Tech Serve Solutions supplies this compound for research and development purposes.
- IUPAC
- N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
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Ion Channel Research
Benzamil hydrochloride hydrate serves as a selective inhibitor of epithelial sodium channels (ENaC). It is widely used in electrophysiology studies to elucidate the role of these channels in various physiological processes.
Cell Signaling Studies
This compound is instrumental in understanding cellular signaling cascades involving sodium transport. Researchers utilise it to investigate how sodium channel activity impacts cellular responses and disease mechanisms.
Neuroscience Research
In neuroscience, benzamil hydrochloride hydrate aids in the study of neuronal excitability and the function of sodium channels in the central nervous system. Its selectivity makes it useful for dissecting specific channel subtypes.
| Molecular weight | 356.21 (anhydrous basis) |
|---|---|
| Empirical formula | C13H14ClN7O · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | methanol: soluble10 mg/mLDMSO: >20 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzamil hydrochloride hydrate used for?
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Benzamil hydrochloride hydrate is primarily used as a research chemical for studying ion channels, cell signaling, and neuroscience, particularly its role as a modulator of voltage-gated sodium channels.
What is the CAS number and formula for Benzamil hydrochloride hydrate?
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The CAS number for the anhydrous form is 161804-20-2. The formula is C13H14ClN7O · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzamil hydrochloride hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Benzamil hydrochloride hydrate be handled?
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Benzamil hydrochloride hydrate is a Warning substance that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, in a well-ventilated area. Store at 2-8°C.
Is Benzamil hydrochloride hydrate a controlled substance?
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The provided data does not indicate that Benzamil hydrochloride hydrate is a controlled substance.
How is Benzamil hydrochloride hydrate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Benzamil hydrochloride hydrate is carefully packed according to international shipping regulations for chemical export.
How can I request a sample or quote for Benzamil hydrochloride hydrate?
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To request a sample or quote, please contact our sales department through the provided contact information on our website.
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