Benazepril hydrochloride

CAS 86541-74-4C24H28N2O5 · HClCell Biology

Benazepril hydrochloride (CAS 86541-74-4, C24H28N2O5 · HCl) is a white to off-white solid with a molecular weight of 460.95 g/mol. It is an angiotensin-converting enzyme (ACE) inhibitor, primarily used as a pharmaceutical intermediate in the synthesis of medications for managing hypertension and congestive heart failure. Benazepril hydrochloride is a key component in drug discovery and development, particularly within cardiovascular research.

IUPAC: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

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Benazepril hydrochloride (C24H28N2O5 · HCl) — chemical structure, CAS 86541-74-4; Life Science, fine chemical supplied by Tech Serve Solutions

Angiotensin MetabolismBioactive Small MoleculesCell BiologyNeuropeptidesNovartisPeptides and Proteins

01 /Applications

Pharmaceutical Intermediate

Benazepril hydrochloride serves as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is integral to the production of ACE inhibitor medications used for treating cardiovascular conditions such as hypertension.

Research and Development

This compound is widely utilised in pharmaceutical research and development for exploring new therapeutic agents and understanding cardiovascular mechanisms. Its role in angiotensin metabolism makes it a valuable tool for biochemical and pharmacological studies.

Drug Discovery

As an approved therapeutic agent itself, Benazepril hydrochloride is also a subject of study for potential new applications or improved formulations within drug discovery programs. It aids in the development of advanced cardiovascular treatments.

02 /Properties

Molecular weight	460.95
Empirical formula	C24H28N2O5 · HCl
Assay	≥98% (HPLC)
Form	solid
Solubility	H2O: >5 mg/mL

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86541-74-4

MDL number

MFCD00895734

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Benazepril hydrochloride used for?

Benazepril hydrochloride is primarily used as a pharmaceutical intermediate in the synthesis of ACE inhibitor medications for managing hypertension and congestive heart failure, and in research and development for cardiovascular studies.

What are the CAS number and formula for Benazepril hydrochloride?

The CAS number for Benazepril hydrochloride is 86541-74-4, and its formula is C24H28N2O5 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Benazepril hydrochloride with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.

What safety precautions should be taken when handling Benazepril hydrochloride?

When handling Benazepril hydrochloride, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified as WGK Germany 2.

How is Benazepril hydrochloride packed and exported?

Benazepril hydrochloride is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to international shipping regulations for fine chemicals.