Alverine citrate salt
Alverine citrate salt (CAS: 5560-59-8), with the molecular formula C20H27N · C6H8O7 and a molecular weight of 473.56 g/mol, is a nitrogen-containing organic compound. It serves as a valuable building block in chemical synthesis. Its applications are primarily focused on pharmacological research, including studies investigating its synergistic effects with antifungal agents and its efficacy in managing symptoms of irritable bowel syndrome.
- IUPAC
- N-Ethyl-3,3′-diphenyldipropylamine,NSC 35459
- Synonyms
- N-Ethyl-3,3′-diphenyldipropylamine citrate, NSC 35459
Pharmacological Activity Studies
Alverine citrate salt is utilised in research exploring its pharmacological activities. This includes investigations into potential synergism with antifungal medications like fluconazole against specific yeast strains.
Gastrointestinal Research
Studies have examined the efficacy of combining alverine citrate with simeticone for the relief of abdominal pain, particularly in the context of irritable bowel syndrome.
Metabolic Pathway Screening
The compound is employed in nutrient-sensitized screening assays to identify drugs that can alter cellular energy metabolism, shifting it from mitochondrial respiration towards glycolysis.
Signal Transduction Research
Alverine citrate salt is used in research that examines drug effects from the perspective of signal transduction networks, contributing to a deeper understanding of cellular communication pathways.
Cytotoxicity Enhancement Studies
Research has investigated how alverine citrate salt can enhance the cytotoxic effects of proteasome inhibitors, such as MG132, in cellular models.
Smooth Muscle Mechanism Investigation
The compound is utilised to study its mechanism of action on phasic smooth muscles, providing insights into its physiological effects.
| Molecular weight | 473.56 |
|---|---|
| Empirical formula | C20H27N · C6H8O7 |
| Application | Used for studies of pharmacological activity including:• Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans1• Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome2• Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis3• Drug effects viewed from a signal transduction network perspective4• Enhanced cytotoxic effect of proteasome inhibitor MG1325• Mechanism of action on phasic smooth muscles6 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Alverine citrate salt used for?
+
Alverine citrate salt is primarily used for studies of pharmacological activity, including investigations into synergism with antifungal agents, efficacy in combination with simeticone for abdominal pain, nutrient-sensitized screening for drugs impacting energy metabolism, signal transduction research, and studies on smooth muscle mechanisms.
What are the CAS number and formula for Alverine citrate salt?
+
The CAS number for Alverine citrate salt is 5560-59-8, and its empirical formula (Hill notation) is C20H27N · C6H8O7.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Alverine citrate salt as a research grade chemical. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
What are the safety and handling recommendations for Alverine citrate salt?
+
Handling Alverine citrate salt requires appropriate personal protective equipment, including eyeshields and gloves. A P1 (EN143) or N95 (US) type respirator filter is recommended for respiratory protection. The compound is classified with a WGK Germany of 3, indicating a high hazard to water.
How is Alverine citrate salt packed and shipped?
+
Alverine citrate salt is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a sample or quote for Alverine citrate salt?
+
To request a sample or a quotation for Alverine citrate salt, please contact our sales department through the TSS website or by phone. Our team will assist you with your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis