8-Anilino-1-naphthalenesulfonic acid
8-Anilino-1-naphthalenesulfonic acid (CAS: 82-76-8), with the molecular formula C6H5NHC10H6SO3H and a molecular weight of 299.34 g/mol, is a naphthalene derivative commonly employed as a fluorescent probe. It is known for its sensitivity to the microenvironment, making it valuable in biochemical and cell biology research for studying protein conformation and membrane dynamics. Supplied as a powder, this compound is a key reagent in various analytical applications.
- IUPAC
- N-Phenyl peri acid,ANS,ANSA
- Synonyms
- N-Phenyl peri acidANSANSA

Fluorescent Probe
8-Anilino-1-naphthalenesulfonic acid serves as a sensitive fluorescent probe. Its fluorescence properties change in response to environmental polarity, making it useful for investigating protein structure, enzyme activity, and membrane fluidity.
Biochemical Research
This compound is utilized in biochemical studies to probe hydrophobic interactions and conformational changes in biological macromolecules. It can bind to hydrophobic regions of proteins, altering its fluorescence emission.
Cell Biology Applications
In cell biology, it is used to study cellular environments, particularly within membranes and hydrophobic pockets of cellular components. Its lipophilic nature allows for interaction with lipid bilayers and protein structures.
| Molecular weight | 299.34 |
|---|---|
| Linear formula | C6H5NHC10H6SO3H |
| Assay | ≥97% (HPLC) |
| Form | powder |
| Solubility | DMF: soluble50 mg/mL |
| Impurities tested | <1% acetone |
| Melting point | 215-217 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Anilino-1-naphthalenesulfonic acid used for?
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8-Anilino-1-naphthalenesulfonic acid is primarily used as a fluorescent probe in biochemical and cell biology research to study protein conformation, enzyme activity, and membrane dynamics due to its sensitivity to environmental polarity.
What is the CAS number and formula for 8-Anilino-1-naphthalenesulfonic acid?
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The CAS number is 82-76-8 and the molecular formula is C6H5NHC10H6SO3H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8-Anilino-1-naphthalenesulfonic acid with an assay of ≥97% (HPLC). It is suitable for research and laboratory use; TSS does not represent it as USP, BP, EP, or pharmaceutical grade.
How should 8-Anilino-1-naphthalenesulfonic acid be handled?
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8-Anilino-1-naphthalenesulfonic acid is classified as hazardous. It may cause skin and eye irritation. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information. The WGK Germany is 3.
How is 8-Anilino-1-naphthalenesulfonic acid packed and shipped?
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This chemical is typically supplied as a powder and is carefully packaged for secure domestic and international export, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or sample for 8-Anilino-1-naphthalenesulfonic acid?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing your contact details and the product CAS number (82-76-8).
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