6-Quinolineboronic acid pinacol ester
6-Quinolineboronic acid pinacol ester (CAS: 406463-06-7, C15H18BNO2) is a versatile organoboronate ester. It functions as a key building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling. Its quinoline core and pinacol boronate ester functionality make it valuable for constructing complex heterocyclic molecules used in pharmaceuticals, agrochemicals, and materials science. This compound offers reliable reactivity for researchers and industrial chemists.
- IUPAC
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline,6-Quinolylboronic acid pinacol ester
- Synonyms
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline6-Quinolylboronic acid pinacol ester
Suzuki-Miyaura Coupling Reagent
This pinacol ester serves as an excellent coupling partner in Suzuki-Miyaura reactions for forming carbon-carbon bonds. It enables the facile introduction of the quinoline moiety into diverse organic frameworks.
Heterocyclic Compound Synthesis
Utilised in the synthesis of complex heteroaryl compounds containing the quinoline scaffold. These structures are often found in biologically active molecules and advanced materials.
Medicinal Chemistry Research
A valuable intermediate for medicinal chemists exploring novel drug candidates. The quinoline structure is a prevalent motif in many pharmaceutical agents.
Materials Science
Can be incorporated into the design of organic electronic materials, such as those used in OLEDs or sensors, due to the electronic properties of the quinoline system.
| Molecular weight | 255.12 |
|---|---|
| Empirical formula | C15H18BNO2 |
| Assay | 97% |
| Melting point | 62-66 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Quinolineboronic acid pinacol ester used for?
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6-Quinolineboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling for constructing complex heterocyclic molecules.
What is the CAS number and molecular formula?
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The CAS number is 406463-06-7 and the molecular formula is C15H18BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. This product is not graded as USP, BP, or EP.
How should 6-Quinolineboronic acid pinacol ester be handled safely?
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This compound is a Warning substance, classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with a dust mask type N95 (US), eyeshields, and gloves in a well-ventilated area. Follow precautionary statements P261 and P305 + P351 + P338.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team through the website to request a sample or a quotation for 6-Quinolineboronic acid pinacol ester.
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