6-Thioguanine
6-Thioguanine (CAS 154-42-7; C5H5N5S; MW: 167.19) is a purine derivative commonly employed as a building block in chemical synthesis. It functions as a key intermediate in the preparation of various heterocyclic compounds. Its purine structure makes it valuable for researchers investigating nucleoside analogues and related biochemical pathways. TSS supplies this compound in a reliable 'purum' grade for laboratory and research applications.
- IUPAC
- 2-Amino-6-mercaptopurine,2-Amino-6-purinethiol
- Synonyms
- 2-Amino-6-mercaptopurine2-Amino-6-purinethiol
Chemical Synthesis Intermediate
Serves as a crucial building block for the synthesis of complex heterocyclic compounds and modified nucleosides. Its purine scaffold is integral in creating novel molecular structures for research.
Research and Development
Utilised in biochemical research, particularly in the study of purine metabolism and nucleoside analogue development. Essential for exploring potential therapeutic agents and understanding biological processes.
Organic Synthesis
A versatile reagent in organic chemistry for constructing molecules with specific biological or material properties. Enables the introduction of the thiopurine moiety into larger molecular frameworks.
| Molecular weight | 167.19 |
|---|---|
| Empirical formula | C5H5N5S |
| Assay | ≥96% (HPLC) |
| Grade | purum |
| Impurities tested | ≤3% guanine |
| Melting point | ≥300 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Thioguanine used for?
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6-Thioguanine (CAS 154-42-7) is primarily used as a building block in chemical synthesis and in biochemical research, particularly for the study of purine analogues and related pathways.
What is the CAS number and chemical formula for 6-Thioguanine?
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The CAS number for 6-Thioguanine is 154-42-7, and its chemical formula is C5H5N5S.
What grade and purity does Tech Serve Solutions supply for 6-Thioguanine?
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Tech Serve Solutions supplies 6-Thioguanine with a purity of ≥96% (HPLC) in a 'purum' grade. This product is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 6-Thioguanine be handled safely?
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6-Thioguanine is classified as acutely toxic (H301) and requires careful handling. Recommended personal protective equipment includes eyeshields, faceshields, gloves, and a P2 respirator. Handle only in a well-ventilated area or fume hood. Consult the Safety Data Sheet (SDS) for comprehensive safety information.
Is 6-Thioguanine a controlled substance?
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The provided data does not indicate that 6-Thioguanine is a controlled substance under standard chemical regulations.
How is 6-Thioguanine packed and shipped?
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6-Thioguanine is shipped according to international regulations for hazardous materials (UN 2811, Class 6.1, Packing Group III). Packaging details are available upon request, adhering to safety and export standards.
How can I request a sample or quote for 6-Thioguanine?
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To request a sample or a quote for 6-Thioguanine, please contact our sales department through the website or via email, specifying the quantity and your shipping details.
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