6-Methoxyindole
6-Methoxyindole (CAS: 3189-13-7), with the molecular formula C9H9NO and a molecular weight of 147.17 g/mol, is a chemical intermediate utilised in various synthesis pathways. Its primary applications lie in the preparation of novel compounds with potential biological activities, including anticancer agents, immunomodulators, and inhibitors of key enzymes like VEGFR-2 and interleukin-2 inducible T cell kinase. This indole derivative serves as a foundational building block in complex organic synthesis.
- IUPAC
- NSC 92517
Anticancer Agent Synthesis
6-Methoxyindole is employed as a reactant in the synthesis of diindolyloxyindoles and 3-aroylindoles, which have demonstrated potential as anticancer agents.
Immunomodulator Precursor
It serves as a reactant for preparing pyridyl-ethenyl-indoles, which are investigated as potential anticancer immunomodulators.
Enzyme Inhibitor Development
The compound is used in the synthesis of indolylindazoles and indolylpyrazolopyridines that act as inhibitors of interleukin-2 inducible T cell kinase.
Antiviral Compound Synthesis
6-Methoxyindole is a reactant in the preparation of benzoylpiperazinyl-indolyl ethane dione derivatives, which are investigated for their potential as HIV-1 inhibitors.
Enzyme Inhibitor Synthesis (VEGFR-2)
It is utilised as a reactant for the synthesis of heteroaryl ketones, which function as VEGFR-2 inhibitors.
| Molecular weight | 147.17 |
|---|---|
| Empirical formula | C9H9NO |
| Assay | 98% |
| Application | • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• Reactant for synthesis of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors3• Reactant for preparation of diindolyloxyindoles as anticancer agents4• Reactant for preparation of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors5• Reactant for preparation of 3-aroylindoles as anticancer agents6• Reactant for preparation of indolyl and isoquinolinyl anthranilates as PPARδ partial agonists7• Reactant for preparation of heteroaryl ketones as VEGFR-2 inhibitors8 |
| Melting point | 90-92 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Methoxyindole used for?
+
6-Methoxyindole is used as a reactant in the synthesis of various biologically active compounds, including anticancer agents, immunomodulators, and enzyme inhibitors such as those targeting VEGFR-2 and interleukin-2 inducible T cell kinase.
What is the CAS number and molecular formula for 6-Methoxyindole?
+
The CAS number for 6-Methoxyindole is 3189-13-7, and its molecular formula is C9H9NO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 6-Methoxyindole with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 6-Methoxyindole be handled safely?
+
6-Methoxyindole is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be used. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
Can Tech Serve Solutions export 6-Methoxyindole globally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, including 6-Methoxyindole.
How can I request a sample or quote for 6-Methoxyindole?
+
Please contact our sales team via the website or email to request a sample or a quotation for 6-Methoxyindole.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis