6-Mercaptohexanoic acid
6-Mercaptohexanoic acid (CAS: 17689-17-7), with the molecular formula C6H12O2S and a molecular weight of 148.22 g/mol, is a valuable thiol-functional organic compound. It is primarily utilised in chemical synthesis and materials science. Its applications include the preparation of functionalised gold nanoparticles and the formation of self-assembled monolayers (SAMs) with tunable surface properties, making it instrumental in advanced micro/nanoelectronic and self-assembly material research.
- IUPAC
- MHA

Nanoparticle Functionalization
Used to prepare thiol-functionalized gold nanoparticles through ligand exchange with pre-stabilized nanoparticles. These functionalized nanoparticles find applications in various scientific research areas.
Self-Assembled Monolayers (SAMs)
This compound enables the creation of hydrophilic SAMs, which can be further modified with amine and alcohol groups to introduce complex functionalities. These SAMs are key in developing advanced surface chemistries.
Colloidal Nanoparticle Control
6-Mercaptohexanoic acid can be employed to precisely manage the aggregation rate of gold colloidal nanoparticles, offering control through pH adjustments.
| Molecular weight | 148.22 |
|---|---|
| Empirical formula | C6H12O2S |
| Assay | 90% |
| Density | 1.0715 g/mL at 25 °C |
| Refractive index | n20/D 1.4846 |
| Storage temperature | −20°C |
| Application | Used to prepare thiol-functionalized 1.5 nm gold nanoparticles via a ligand exchange process with triphenylphosphine-stabilized nanoparticles.1 This compound is used in self-assembly to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized2 with various amines and alcohols to introduce more complex end groups. Can also be used to control the rate of aggregation of gold colloidal nanoparticles using pH.3 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Ace(24310) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Mercaptohexanoic acid used for?
+
6-Mercaptohexanoic acid is used in the preparation of thiol-functionalized gold nanoparticles, in the formation of self-assembled monolayers (SAMs) with tunable surface properties, and to control the aggregation rate of gold colloidal nanoparticles.
What are the CAS number and formula for 6-Mercaptohexanoic acid?
+
The CAS number is 17689-17-7 and the empirical formula is C6H12O2S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 6-Mercaptohexanoic acid with a minimum assay of 90%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 6-Mercaptohexanoic acid be handled safely?
+
6-Mercaptohexanoic acid is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always wear appropriate personal protective equipment, including eyeshields and gloves, and handle in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling guidelines.
How is 6-Mercaptohexanoic acid packed, shipped, and exported?
+
We ensure secure and compliant packaging for all our chemicals, adhering to international shipping regulations for safe global export. Specific packaging details are confirmed upon order.
How can I request a sample or quote for 6-Mercaptohexanoic acid?
+
To request a sample or a detailed quote, please contact our sales team through the website or by email, specifying the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis