Talampanel
Talampanel (CAS: 161832-65-1, C19H19N3O3) is a chemical compound with a molecular weight of 337.37 g/mol. Supplied by Tech Serve Solutions as a white to beige powder with an assay of ≥97% (HPLC), Talampanel is primarily used in scientific research, particularly within neuroscience and cell biology. It functions as an antagonist for AMPA and kainate receptors, playing a role in understanding excitatory amino acid neurotransmission.
- IUPAC
- (R)-(-)-1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine,GYKI 53773,LY 300164,LY300164

Neuroscience Research
Talampanel is employed as a research tool to investigate the role of AMPA and kainate receptors in neural pathways. Its antagonist properties aid in studying excitatory neurotransmission and its involvement in various neurological processes.
Cell Biology Studies
This compound is utilised in cell biology to explore cellular signalling mechanisms related to glutamate receptors. Researchers use Talampanel to modulate receptor activity and observe downstream cellular effects.
Pharmacological Investigations
As a selective antagonist, Talampanel is valuable in pharmacological studies aimed at understanding the function and therapeutic potential of targeting AMPA/kainate receptors.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C19H19N3O3 |
| Assay | ≥97% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble15 mg/mL, clear |
| Optical activity | [α]/D -280 to -340°, c = 1 in methanol |
| Storage temperature | 2-8°C |


Hazard statements
- H301Toxic if swallowed
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P501Dispose of contents and container per local regulations
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-50/53 |
| Safety statements (S) | 45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Talampanel used for?
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Talampanel is used in scientific research, particularly within neuroscience and cell biology, as an antagonist for AMPA and kainate receptors to study excitatory neurotransmission.
What is the CAS number and molecular formula for Talampanel?
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The CAS number for Talampanel is 161832-65-1, and its molecular formula is C19H19N3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Talampanel with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Talampanel be handled and stored?
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Talampanel is classified as Toxic if swallowed and Very toxic to aquatic life with long lasting effects. It should be handled with appropriate personal protective equipment in a well-ventilated area and stored at 2-8°C. Avoid release to the environment.
How is Talampanel packed and exported by TSS?
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Talampanel is carefully packed to maintain its integrity during transit and is exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations.
How can I request a sample or quote for Talampanel?
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To request a sample or a quote for Talampanel, please contact our sales team through the website or by phone, providing your specific requirements.
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