Tafenoquine succinate
Tafenoquine succinate (CAS 106635-81-8), with the molecular formula C24H28F3N3O3 · C4H6O4 and a molecular weight of 581.58, is a potent compound primarily investigated for its antimalarial properties. It functions as an 8-aminoquinoline derivative, exhibiting activity against various stages of the malaria parasite lifecycle. Tafenoquine succinate is employed in research settings for studying drug resistance mechanisms and evaluating new therapeutic strategies against parasitic diseases.
- IUPAC
- N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine,SB-252263,WR 238605
- Synonyms
- N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine succinate
Antimalarial Research
Investigated for its efficacy against Plasmodium species, particularly in radical cure and prophylaxis of malaria. Its mechanism involves disrupting parasitic DNA and interfering with essential metabolic pathways.
Cell Biology Studies
Utilised in cell-based assays to explore mechanisms of drug action and resistance in parasitic infections. It serves as a tool compound for understanding cellular responses to antimalarial agents.
Drug Discovery and Development
Serves as a reference compound in the development of new antimalarial drugs and related therapeutic agents. Its known efficacy profile aids in screening and optimising novel chemical entities.
| Molecular weight | 581.58 |
|---|---|
| Empirical formula | C24H28F3N3O3 · C4H6O4 |
| Assay | ≥95% (HPLC) |
| Solubility | DMSO: soluble5 mg/mL (clear solution) |
| Storage temperature | 2-8°C |
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tafenoquine succinate used for?
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Tafenoquine succinate is primarily researched for its antimalarial properties, including radical cure and prophylaxis of malaria, and is used as a tool compound in cell biology studies and drug discovery.
What are the CAS number and formula for Tafenoquine succinate?
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The CAS number for Tafenoquine succinate is 106635-81-8, and its empirical formula is C24H28F3N3O3 · C4H6O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tafenoquine succinate with a purity of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Tafenoquine succinate be handled and stored?
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According to the provided safety data, Tafenoquine succinate has a WGK Germany rating of 3, indicating it is hazardous to water. It should be stored at 2-8°C, desiccated, and handled with appropriate safety precautions to avoid environmental release.
How is Tafenoquine succinate packed and shipped?
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Tafenoquine succinate is typically packed in desiccated containers and stored at 2-8°C. TSS ensures secure export of laboratory chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for Tafenoquine succinate?
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To request a sample or a quote for Tafenoquine succinate, please contact our sales team through the website or by phone, providing the product name and CAS number (106635-81-8).
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