TTNPB
TTNPB (CAS: 71441-28-6), a potent retinoid derivative with the molecular formula C24H28O2 and a molecular weight of 348.48 g/mol, is a valuable tool in biomedical research. It functions as a selective agonist for retinoic acid receptors (RARs) and retinoid X receptors (RXRs). TTNPB is primarily utilized in transcriptional assays and for investigating gene regulation, cell differentiation, and various cellular processes, particularly within the fields of cell biology and neuroscience.
- IUPAC
- 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid,Arotinoid acid
- Synonyms
- 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acidArotinoid acid
Transcriptional Assays
TTNPB is employed in 293T cells for conducting transcriptional assays, aiding in the study of gene regulation mechanisms. This application is crucial for understanding how specific cellular pathways are activated or modulated.
RAR Agonist in Cell Culture
As a RAR-agonist, TTNPB has been used in cultured human cord blood CD34+CD38-lin- cells. This research application is relevant for investigating hematopoietic stem cell differentiation and function.
Research in Cell Biology
The compound serves as a key reagent in cell biology research, particularly in studies concerning cell signaling, differentiation, and gene expression. Its specific activity targets nuclear receptors involved in these processes.
Neuroscience and Gene Regulation Studies
TTNPB's ability to modulate gene expression through nuclear receptors makes it a valuable tool for research in neuroscience and gene regulation. It aids in understanding complex biological pathways.
| Molecular weight | 348.48 |
|---|---|
| Empirical formula | C24H28O2 |
| Solubility | chloroform/methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to light yellowethanol: soluble10 mMDMSO: soluble25 mM |
| Storage temperature | −20°C |
| Application | TTNPB has been used for transcriptional assays in 293T cells4. It has also been used as a RAR-agonist in cultured human cord blood CD34+CD38-lin- cells5. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 60-61-36/37/38 |
| Safety statements (S) | 53-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TTNPB used for?
+
TTNPB is used for transcriptional assays in cells, as a RAR-agonist in cell culture, and in research within cell biology, cell signaling, neuroscience, gene regulation, and studies involving PPAR and RXR regulators.
What are the CAS number and formula for TTNPB?
+
The CAS number for TTNPB is 71441-28-6, and its molecular formula is C24H28O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies TTNPB as a research-grade chemical. The specific assay and purity are detailed on the Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety hazards associated with TTNPB?
+
TTNPB is classified with Danger as the signal word. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), and H360 (May damage fertility or the unborn child). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, is essential for safe handling.
How is TTNPB packed, shipped, and exported?
+
TTNPB is typically packed in suitable containers to maintain its integrity during transit. Tech Serve Solutions, a global supplier and exporter, adheres to all relevant regulations for the safe and compliant shipment of chemicals worldwide.
How can I request a sample or quote for TTNPB?
+
To request a sample or a quote for TTNPB, please contact the Tech Serve Solutions sales department via our website or direct inquiry channels, providing your specific requirements.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis