6-Maleimidohexanoic acid
6-Maleimidohexanoic acid (CAS 55750-53-3, C10H13NO4) is a versatile organic building block with a molecular weight of 211.21 g/mol. This compound serves as a key spacer molecule in bioconjugation strategies, facilitating the linkage of different molecular entities. It is frequently employed in conjunction with N-hydroxysuccinimide esters, acting as a bifunctional cross-linking reagent for applications in chemical synthesis and research.
- IUPAC
- 6-Maleimidocaproic acid,N-Maleoyl-6-aminocaproic acid,N-(5-Carboxypentyl)maleimide
- Synonyms
- 6-Maleimidocaproic acidN-Maleoyl-6-aminocaproic acidN-(5-Carboxypentyl)maleimide
Bioconjugation Spacer
6-Maleimidohexanoic acid functions as a critical spacer in the development of drug conjugates and other biomolecular constructs. Its chemical structure allows for controlled linkage between different functional groups.
Bifunctional Cross-linking
When used with N-hydroxysuccinimide esters, this compound acts as a bifunctional cross-linking reagent. This enables the covalent attachment of molecules, essential in various biochemical and synthetic applications.
Chemical Synthesis
As an organic building block, 6-Maleimidohexanoic acid is utilised in complex organic synthesis pathways. Its carboxylic acid and maleimide functionalities offer reactive sites for diverse chemical transformations.
| Molecular weight | 211.21 |
|---|---|
| Empirical formula | C10H13NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Application | 6-Maleimidohexanoic acid may be used as a spacer in the construction of drug and other types of bioconjugates. 6-Maleimidohexanoic acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking reagent. |
| Melting point | 86-91 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Maleimidohexanoic acid used for?
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6-Maleimidohexanoic acid is primarily used as a spacer in the construction of drug and other bioconjugates, and as a bifunctional cross-linking reagent in conjunction with N-hydroxysuccinimide esters for chemical synthesis and research applications.
What is the CAS number and chemical formula for 6-Maleimidohexanoic acid?
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The CAS number for 6-Maleimidohexanoic acid is 55750-53-3, and its chemical formula is C10H13NO4.
What grade and purity does Tech Serve Solutions supply for 6-Maleimidohexanoic acid?
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Tech Serve Solutions supplies 6-Maleimidohexanoic acid with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 6-Maleimidohexanoic acid be handled safely?
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Handle 6-Maleimidohexanoic acid with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes, as it can cause skin irritation, serious eye damage, and respiratory irritation (H315-H318-H335).
How is 6-Maleimidohexanoic acid packed, shipped, and exported?
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6-Maleimidohexanoic acid is carefully packed to ensure product integrity during transit. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, providing worldwide shipping.
How can I request a quote or sample of 6-Maleimidohexanoic acid?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (55750-53-3).
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