6-Iodoquinoline
6-Iodoquinoline (CAS: 13327-31-6; Formula: C9H6IN; Molar Mass: 255.06 g/mol) is a halogenated heterocyclic building block. It serves as a key reactant in advanced chemical synthesis, notably in copper-catalyzed N-arylation reactions under mild conditions. This compound is essential for constructing complex molecular architectures in research and development settings, particularly within organic chemistry and materials science.
N-Arylation Reactions
6-Iodoquinoline acts as a crucial substrate in copper(I) iodide-catalyzed N-arylation reactions. It enables the efficient formation of carbon-nitrogen bonds, a fundamental transformation in organic synthesis, particularly when employing ligands such as 2-pyridinyl β-ketones.
Organic Synthesis Intermediate
As a versatile heterocyclic building block, 6-Iodoquinoline is utilised in the synthesis of more complex organic molecules. Its iodo-substitution provides a reactive handle for various coupling reactions and functional group transformations.
Research and Development
This compound finds application in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chemical entities. Its specific structure lends itself to the creation of diverse quinoline-based scaffolds.
| Molecular weight | 255.06 |
|---|---|
| Empirical formula | C9H6IN |
| Application | Reactant for:• Room temperature CuI-catalyzed N-arylation using 2-pyridinyl β-ketones ligands1 |
| Melting point | 86-90 °C |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Iodoquinoline used for?
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6-Iodoquinoline is primarily used as a reactant in organic synthesis, particularly for copper-catalyzed N-arylation reactions and as a general building block for constructing complex molecules, especially within research and development.
What are the CAS number and formula for 6-Iodoquinoline?
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The CAS number for 6-Iodoquinoline is 13327-31-6, and its empirical formula (Hill notation) is C9H6IN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Iodoquinoline with a purity typically between 86-90 °C (Melting Point). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade; it is suitable for research and general chemical synthesis applications.
How should 6-Iodoquinoline be handled safely?
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6-Iodoquinoline is classified as Dangerous (GHS05, GHS07, Signal Word: Danger). It is harmful if swallowed (H302) and causes serious eye damage (H318). Always wear appropriate personal protective equipment, including eye protection (P280, P305 + P351 + P338), and handle in a well-ventilated area. In case of contact with eyes, rinse cautiously with water for several minutes.
Does Tech Serve Solutions export 6-Iodoquinoline?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 6-Iodoquinoline, serving customers worldwide.
How can I request a sample or quote for 6-Iodoquinoline?
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To request a sample or a quote for 6-Iodoquinoline, please contact our sales department via the website or directly through the provided contact details.
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