5-Methylindole
5-Methylindole (CAS 614-96-0, C9H9N, MW: 131.17) is a key heterocyclic building block supplied by Tech Serve Solutions. This indole derivative serves as a crucial reactant in the synthesis of a wide array of complex organic molecules. Its primary applications lie in the preparation of pharmaceutical intermediates and potential therapeutic agents, demonstrating its significance in advanced chemical research and development.
- IUPAC
- NSC 522562
Pharmaceutical Intermediate Synthesis
5-Methylindole is utilized as a precursor for synthesizing various pharmaceutically active compounds, including 2-oxo-1-pyrrolidine analogues and potential anticancer immunomodulators.
Antifungal Agent Preparation
The compound serves as a reactant in the preparation of agents designed for antifungal activity, contributing to the development of new treatments against fungal infections.
Diabetes Management Agents
It is employed in the synthesis of sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors, which are important in managing hyperglycemia associated with diabetes.
Kinase Inhibitor Development
5-Methylindole is a building block for developing inhibitors of kinases such as IL2-inducible T-cell kinase (ITK) and Checkpoint 1 kinase, relevant in immunological and cellular processes.
Antiviral and Receptor Modulator Synthesis
It acts as a reactant in creating inhibitors of HIV-1 attachment and agonists of the histamine H4 receptor, alongside monoamine reuptake inhibitors.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C9H9N |
| Assay | 99% |
| Application | Reactant for preparation of:• Pharmaceutically active 2-oxo-1-pyrrolidine analogues1• Potential anticancer immunomodulators2• Preparation of antifungal agents3• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes4• IL2-inducible T-cell kinase (ITK) inhibitors5• Checkpoint 1 kinase inhibitors6• CRTh2 antagonists7• Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment8• Agonists of the histamine H4 receptor9• Monoamine reuptake inhibitors10 |
| Melting point | 60-62 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methylindole used for?
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5-Methylindole (CAS 614-96-0) is primarily used as a reactant in the synthesis of various pharmaceutical intermediates and potential therapeutic agents, including immunomodulators, antifungal agents, and enzyme inhibitors.
What is the CAS number and formula for 5-Methylindole?
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The CAS number for 5-Methylindole is 614-96-0, and its molecular formula is C9H9N.
What grade and purity does Tech Serve Solutions supply for 5-Methylindole?
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Tech Serve Solutions supplies 5-Methylindole with a minimum purity of 99%. This is a technical/research grade material and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 5-Methylindole be handled safely?
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5-Methylindole is classified as a Warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Safe handling requires wearing a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation.
How is 5-Methylindole packed and exported?
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5-Methylindole is packed according to industry best practices for chemical reagents and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample of 5-Methylindole?
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Please use the 'Request a Quote' or 'Request a Sample' button on the product page, or contact our sales team directly to discuss your requirements for 5-Methylindole.
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