5-Methylhydantoin
5-Methylhydantoin (CAS: 616-03-5), with the molecular formula C4H6N2O2 and a molecular weight of 114.10 g/mol, is a heterocyclic organic compound. This chemical serves as a key reactant in various synthetic processes, including the preparation of N-chlorohydantoins and applications in Mitsunobu reactions. It is also utilised in biochemical research for enzymatic conversions and racemization, particularly in the production of L-amino acids.
- IUPAC
- 5-Methyl-2,4-imidazolidinedione
N-Chlorohydantoin Preparation
5-Methylhydantoin is a valuable precursor for the synthesis of N-chlorohydantoins, which are often employed as chlorinating agents in organic chemistry.
Mitsunobu Reaction Substrate
This compound can participate in the Mitsunobu reaction, a versatile method for the inversion of stereochemistry or the formation of carbon-heteroatom bonds under mild conditions.
Amino Acid Bioconversion
Utilised in enzymatic processes, 5-Methylhydantoin can be converted into L-amino acids by specific microbial strains such as *Pseudomonas putida*.
Enzymatic Racemization Studies
It serves as a substrate in studies involving enzymatic racemization, with enzymes like D-hydantoinase from *Agrobacteria tumefaceins* demonstrating its utility in chiral resolution.
| Molecular weight | 114.10 |
|---|---|
| Empirical formula | C4H6N2O2 |
| Assay | 97% |
| Application | Reactant for: Preparation of N-chlorohydantoins1 The Mitsunobu reaction2 Pseudomonas putida strain allowing conversion into L-amino acids3 D-hydantoinase from Agrobacteria tumefaceins4 Eznymatic racemization5 |
| Melting point | 148-152 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methylhydantoin primarily used for?
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5-Methylhydantoin is used as a reactant for the preparation of N-chlorohydantoins, in Mitsunobu reactions, and in enzymatic conversions for producing L-amino acids and for enzymatic racemization.
What are the CAS number and formula for 5-Methylhydantoin?
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The CAS number for 5-Methylhydantoin is 616-03-5, and its empirical formula is C4H6N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methylhydantoin with a minimum purity of 97%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Methylhydantoin be handled safely?
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5-Methylhydantoin is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure adequate ventilation.
How is 5-Methylhydantoin packed and shipped?
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5-Methylhydantoin is packed in compliance with international shipping regulations. Tech Serve Solutions exports chemicals globally.
How can I request a sample or quote for 5-Methylhydantoin?
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To request a sample or obtain a quote for 5-Methylhydantoin, please contact our sales department through the website or via email, providing your specific requirements.
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