3,5-Diiodosalicylic acid
3,5-Diiodosalicylic acid (CAS: 133-91-5) is a halogenated aromatic carboxylic acid with the molecular formula C7H4I2O3 and a molecular weight of 389.91 g/mol. This compound serves as a valuable building block in organic synthesis and chemical research. Its chemical structure, featuring two iodine atoms and a hydroxyl group ortho to the carboxylic acid, makes it useful for introducing specific functionalities in more complex molecules, particularly in the development of new chemical entities and materials.
- IUPAC
- 2-Hydroxy-3,5-diiodobenzoic acid,3,5-Diiodo-2-hydroxybenzoic acid
- Synonyms
- I2C6H2(OH)CO2H2-Hydroxy-3,5-diiodobenzoic acid3,5-Diiodo-2-hydroxybenzoic acid

Organic Synthesis Intermediate
3,5-Diiodosalicylic acid is frequently employed as a key intermediate in the synthesis of diverse organic compounds. Its reactive functional groups allow for various chemical transformations, facilitating the construction of complex molecular architectures for research and development purposes.
Research and Development
This compound is utilized in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities. It serves as a versatile reagent for reactions requiring specific halogenation patterns and aromatic functionalisation.
Building Block for Specialty Chemicals
The unique structure of 3,5-Diiodosalicylic acid makes it an effective building block for the synthesis of specialty chemicals and advanced materials. Its incorporation into larger structures can impart specific physical or chemical properties.
| Molecular weight | 389.91 |
|---|---|
| Linear formula | I2C6H2(OH)CO2H |
| Assay | 99% |
| Melting point | 220-230 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Diiodosalicylic acid used for?
+
3,5-Diiodosalicylic acid is primarily used as an intermediate in organic synthesis and as a building block in research and development for creating new chemical entities and materials.
What is the CAS number and formula for 3,5-Diiodosalicylic acid?
+
The CAS number is 133-91-5, and its linear formula is I2C6H2(OH)CO2H.
What grade and purity does Tech Serve Solutions supply for 3,5-Diiodosalicylic acid?
+
Tech Serve Solutions supplies 3,5-Diiodosalicylic acid with an assay of 99%. This product is supplied for laboratory and manufacturing use and is not represented as USP, BP, EP, food, or nutraceutical grade.
How should 3,5-Diiodosalicylic acid be handled safely?
+
Handle 3,5-Diiodosalicylic acid with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. It is classified with GHS07 symbol, a Warning signal word, and carries hazard statements H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and may cause respiratory irritation.
Is 3,5-Diiodosalicylic acid a controlled substance?
+
The provided data does not indicate that 3,5-Diiodosalicylic acid is a controlled substance.
How is 3,5-Diiodosalicylic acid exported and shipped?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, shipping products worldwide in compliance with international regulations.
How can I request a sample or quote for 3,5-Diiodosalicylic acid?
+
To request a sample or a quote, please contact our sales department through the details provided on our website.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis