5-Fluoro-2-hydroxypyrimidine
5-Fluoro-2-hydroxypyrimidine (CAS: 2022-78-8), a fluorinated heterocyclic compound with the molecular formula C4H3FN2O and a molecular weight of 114.08 g/mol, serves as a valuable building block in organic synthesis. Its structure, featuring a pyrimidine ring with fluorine and hydroxyl substituents, makes it suitable for applications in the development of novel molecules, particularly within the pharmaceutical and agrochemical sectors. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- 5-Fluoro-2(1H)-pyrimidone
- Synonyms
- 5-Fluoro-2(1H)-pyrimidone
Pharmaceutical Intermediate
This fluorinated pyrimidine derivative is utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique structural features can be incorporated into drug candidates to modulate pharmacokinetic and pharmacodynamic properties.
Agrochemical Synthesis
5-Fluoro-2-hydroxypyrimidine can be employed in the development of new agrochemicals, such as herbicides, fungicides, and insecticides. The fluorine atom often enhances the efficacy and metabolic stability of the target compounds.
Organic Synthesis Building Block
As a versatile building block, it is integral for constructing more complex organic molecules. Researchers and chemists utilise it in diverse synthetic pathways for materials science and discovery chemistry.
Research and Development
This compound is frequently used in research laboratories for exploring novel chemical reactions and synthesising new chemical entities for various scientific investigations.
| Molecular weight | 114.08 |
|---|---|
| Empirical formula | C4H3FN2O |
| Assay | 97% |
| Melting point | 170-174 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-hydroxypyrimidine used for?
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5-Fluoro-2-hydroxypyrimidine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It serves as a key intermediate in creating more complex molecules with potential biological activity.
What are the CAS number and formula for 5-Fluoro-2-hydroxypyrimidine?
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The CAS number for 5-Fluoro-2-hydroxypyrimidine is 2022-78-8, and its empirical formula is C4H3FN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-hydroxypyrimidine with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeial standard.
How should 5-Fluoro-2-hydroxypyrimidine be handled safely?
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Handling requires caution due to its hazardous properties. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, must be worn. Ensure adequate ventilation and avoid dust formation.
Is 5-Fluoro-2-hydroxypyrimidine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Fluoro-2-hydroxypyrimidine, and can accommodate international orders.
How can I request a quote or sample for 5-Fluoro-2-hydroxypyrimidine?
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To request a quote or sample, please contact our sales team through the website or by phone. Specify the product name, CAS number, and the quantity required.
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