5-Ethyl-2′-deoxyuridine
5-Ethyl-2′-deoxyuridine (CAS: 15176-29-1), with the molecular formula C11H16N2O5 and a molecular weight of 256.26, is a nucleoside analog. It functions as a modulator for 5-fluorouracil (5-FU), potentially enhancing its therapeutic index by influencing 5-FU concentrations and offering protection to normal tissues. This compound is primarily utilised in biochemical research and as a reagent in related studies.
- IUPAC
- EUdR,Edoxudine
- Synonyms
- EUdREdoxudine
5-Fluorouracil (5-FU) Modulation
5-Ethyl-2′-deoxyuridine (EUdR) is employed to modulate the efficacy and reduce the toxicity of the chemotherapeutic agent 5-fluorouracil (5-FU). It may help to prolong plasma and intratumoral concentrations of 5-FU.
Pharmacological Research
EUdR serves as a valuable tool in research settings investigating drug metabolism and resistance mechanisms. Its role in altering 5-FU pharmacokinetics makes it a subject of interest for developing improved cancer treatment strategies.
Biochemical Studies
As a nucleoside analog, this compound is used in biochemical assays and studies related to nucleic acid metabolism and cellular processes. Its specific structure allows for targeted investigations within these fields.
| Molecular weight | 256.26 |
|---|---|
| Empirical formula | C11H16N2O5 |
| Storage temperature | −20°C |
| Application | 5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Ethyl-2′-deoxyuridine used for?
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5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (5-FU) modulator. It may enhance the therapeutic index of 5-FU by reducing its catabolism, prolonging plasma and intratumoral concentrations, and protecting normal organs.
What is the CAS number and molecular formula for 5-Ethyl-2′-deoxyuridine?
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The CAS number is 15176-29-1 and the molecular formula is C11H16N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Ethyl-2′-deoxyuridine as a research-grade chemical. We do not represent it as USP, BP, or EP grade.
How should 5-Ethyl-2′-deoxyuridine be handled and stored?
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Handle 5-Ethyl-2′-deoxyuridine with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., type N95 or P1 respirator filter). Store at -20°C as indicated.
Is 5-Ethyl-2′-deoxyuridine a controlled substance?
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The provided data does not indicate that 5-Ethyl-2′-deoxyuridine (CAS: 15176-29-1) is a controlled substance.
How can I request a sample or quote for 5-Ethyl-2′-deoxyuridine?
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Please contact our sales team through the website or by phone to request a sample or a quotation for 5-Ethyl-2′-deoxyuridine.
Does Tech Serve Solutions export 5-Ethyl-2′-deoxyuridine?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Ethyl-2′-deoxyuridine.
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