5-Cyclohexylpentyl β-D-maltoside
5-Cyclohexylpentyl β-D-maltoside (CAS: 250692-65-0), a non-ionic detergent with the formula C23H42O11 and molecular weight 494.57 g/mol. This detergent is characterised by a higher critical micelle concentration (CMC) and increased hydrophobicity compared to its linear analogue. It is primarily utilised in biochemical research for the solubilisation, purification, and crystallisation of membrane-bound proteins while preserving their native structure.
- IUPAC
- CYMAL®-5

Membrane Protein Solubilisation
5-Cyclohexylpentyl β-D-maltoside is effective in solubilising membrane proteins, enabling their extraction from lipid bilayers while maintaining structural integrity for subsequent analysis.
Protein Crystallisation
This non-ionic detergent facilitates the crystallisation of membrane proteins, aiding in the determination of their three-dimensional structures.
Nanodisc Preparations
It serves as a valuable reagent in the preparation of nanodiscs, a system used to study membrane proteins in a lipidic environment.
Biochemical Research Reagent
As a versatile biochemical, it is employed in various research applications, including electrophoresis and peptide analysis, where mild detergent properties are required.
| Molecular weight | 494.57 |
|---|---|
| Empirical formula | C23H42O11 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +51±4°, c = 0.5% in methanol |
| Application | Detergent for the purification and crystallization of membrane-bound proteins in native structure. It has a higher CMC (critical micelle concentration) and is more hydrophobic than the corresponding linear chain analog (C23).1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | non-ionic |
|---|---|
| Mol Wt | micellar average mol wt 32,600 |
| Aggregation Number | 66 |
| Cmc | 2.4-5 mM(20-25°C) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Cyclohexylpentyl β-D-maltoside used for?
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5-Cyclohexylpentyl β-D-maltoside is a non-ionic detergent used for the solubilisation, purification, and crystallisation of membrane-bound proteins in their native structure. It is also utilised in the preparation of nanodiscs for membrane protein research.
What are the CAS number and chemical formula for 5-Cyclohexylpentyl β-D-maltoside?
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The CAS number is 250692-65-0 and the empirical formula (Hill Notation) is C23H42O11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Cyclohexylpentyl β-D-maltoside with a purity of ≥98.0% (TLC). This is a research-grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should 5-Cyclohexylpentyl β-D-maltoside be handled?
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When handling 5-Cyclohexylpentyl β-D-maltoside, it is recommended to wear safety eyewear and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the safety data sheet for detailed handling information.
Is 5-Cyclohexylpentyl β-D-maltoside a hazardous substance?
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According to the Globally Harmonized System (GHS), 5-Cyclohexylpentyl β-D-maltoside has a WGK Germany rating of 3, indicating it is hazardous to water. Always consult the safety data sheet for comprehensive hazard information and safe handling procedures.
How is 5-Cyclohexylpentyl β-D-maltoside packed, shipped, and exported?
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Tech Serve Solutions offers global supply and export of fine chemicals. Specific packaging, shipping, and export details for 5-Cyclohexylpentyl β-D-maltoside are available upon request, adhering to all relevant international regulations.
How can I request a sample or a quote for 5-Cyclohexylpentyl β-D-maltoside?
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To request a sample or a quote for 5-Cyclohexylpentyl β-D-maltoside, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your inquiry.
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