5-Bromo-2-fluoropyridine
5-Bromo-2-fluoropyridine (CAS 766-11-0) is a halogenated pyridine derivative with the molecular formula C5H3BrFN and a molecular weight of 175.99 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoro-5-pyridyl moiety into more complex molecules. Its structure makes it useful in the development of pharmaceuticals and agrochemicals, offering unique reactivity due to the presence of both bromine and fluorine substituents on the pyridine ring.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs). The fluoropyridine core is found in various drug candidates targeting different therapeutic areas, leveraging its electronic properties and metabolic stability.
Agrochemical Development
Serves as a key intermediate in the creation of novel pesticides and herbicides. The introduction of halogenated heterocycles can enhance the biological activity and environmental profile of agrochemical products.
Materials Science Research
Investigated for potential applications in the development of advanced materials. Its unique structural features may be exploited in the synthesis of polymers or functional organic materials.
Organic Synthesis Reagent
A versatile building block for constructing complex organic molecules. It participates in various cross-coupling reactions and nucleophilic substitution reactions, enabling diverse synthetic pathways.
| Molecular weight | 175.99 |
|---|---|
| Empirical formula | C5H3BrFN |
| Assay | 99% |
| Boiling point | 162-164 °C/750 mmHg(lit.) |
| Density | 1.71 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5325(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-fluoropyridine used for?
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5-Bromo-2-fluoropyridine (CAS 766-11-0) is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 5-Bromo-2-fluoropyridine?
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The CAS number is 766-11-0 and the chemical formula is C5H3BrFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-fluoropyridine with a minimum assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 5-Bromo-2-fluoropyridine be handled safely?
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5-Bromo-2-fluoropyridine is classified as a Warning substance with H-statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Always handle with appropriate personal protective equipment, including safety goggles, gloves, and use in a well-ventilated area or fume hood. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Is 5-Bromo-2-fluoropyridine a controlled substance?
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Based on the provided data, 5-Bromo-2-fluoropyridine is not listed as a controlled substance. However, users should always verify local regulations.
How is 5-Bromo-2-fluoropyridine packed and shipped?
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5-Bromo-2-fluoropyridine is packed according to industry standards for chemical safety and compliance. It is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 5-Bromo-2-fluoropyridine?
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To request a sample or a quote for 5-Bromo-2-fluoropyridine, please contact the Tech Serve Solutions sales team through our website or by phone.
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