5′-Amino-5′-deoxythymidine
5′-Amino-5′-deoxythymidine (CAS: 25152-20-9; Formula: C10H15N3O4; MW: 241.24 g/mol) is a valuable nucleoside analogue. This compound serves as a crucial building block in advanced biochemical research and the synthesis of modified oligonucleotides. Its primary applications include site-specific DNA modification and the creation of novel oligonucleotide structures for diverse scientific investigations.

Synthesis of Amide-Conjugated Nucleosides
Utilised as a substrate in the chemical synthesis of amide-conjugated nucleosides and their corresponding analogues for research purposes.
DNA Site-Specific Modification
Employed for introducing modifications at specific sites within DNA molecules, facilitating studies in molecular biology and genetic research.
Production of Modified Oligonucleotides
Used in the creation of modified thymidine dimer oligonucleotide building units, such as those incorporating squaryl groups, for developing novel oligonucleotide analogues.
| Molecular weight | 241.24 |
|---|---|
| Empirical formula | C10H15N3O4 |
| Storage temperature | 2-8°C |
| Application | 5′-Amino-5′-deoxythymidine may be used as a substrate in the synthesis of amide-conjugated nucleosides and their analogues. 5′-Amino-5′-deoxythymidine may be used for DNA 5′-terminal site-specific modification. 5′-Amino-5′-deoxythymidine is used to produce modified thymidine dimer oligonucleotide building units (squaryl groups) to create new oligonucleotide analogues. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5′-Amino-5′-deoxythymidine used for?
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5′-Amino-5′-deoxythymidine is used as a substrate in the synthesis of amide-conjugated nucleosides and their analogues, for DNA 5′-terminal site-specific modification, and to produce modified thymidine dimer oligonucleotide building units.
What are the CAS number and chemical formula for 5′-Amino-5′-deoxythymidine?
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The CAS number is 25152-20-9 and the chemical formula is C10H15N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5′-Amino-5′-deoxythymidine typically for research and laboratory use. The specific assay and purity will be detailed on the Certificate of Analysis provided with your order. TSS does not represent this product as USP, BP, or EP grade.
How should 5′-Amino-5′-deoxythymidine be handled and stored?
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Handle 5′-Amino-5′-deoxythymidine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the chemical at 2-8°C.
Is 5′-Amino-5′-deoxythymidine classified as a hazardous substance?
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The product has a WGK Germany rating of 3, indicating it is highly hazardous to water. Appropriate safety precautions must be taken during handling and disposal.
Can Tech Serve Solutions export 5′-Amino-5′-deoxythymidine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5′-Amino-5′-deoxythymidine. We handle international shipments with expertise.
How can I request a sample or quote for 5′-Amino-5′-deoxythymidine?
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To request a sample or a detailed quote, please contact our sales team directly through our website or by phone, referencing the product name and CAS number (25152-20-9).
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