4-(Trifluoromethyl)phenylacetic acid
4-(Trifluoromethyl)phenylacetic acid (CAS: 32857-62-8; Formula: CF3C6H4CH2CO2H; MW: 204.15) is a valuable organic building block. This carboxylic acid derivative, also known as (α,α,α-Trifluoro-p-tolyl)acetic acid, features a trifluoromethyl group on a phenylacetic acid core. It is primarily utilised in chemical synthesis as an intermediate for the production of more complex organic molecules, particularly in the pharmaceutical and agrochemical sectors.
- IUPAC
- (α,α,α-Trifluoro-p-tolyl)acetic acid
- Synonyms
- (α,α,α-Trifluoro-p-tolyl)acetic acid
Pharmaceutical Intermediates
Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), contributing the trifluoromethylphenylacetic moiety to target drug molecules.
Agrochemical Development
Utilised in the research and development of novel pesticides and herbicides, where the trifluoromethyl group can impart desirable properties such as enhanced lipophilicity and metabolic stability.
Organic Synthesis Reagent
A versatile reagent for introducing the 4-(trifluoromethyl)phenylacetyl group into various organic structures, facilitating the creation of diverse chemical entities.
Material Science Research
Potential applications in the development of specialised polymers or functional materials where its unique electronic and steric properties can be leveraged.
| Molecular weight | 204.15 |
|---|---|
| Linear formula | CF3C6H4CH2CO2H |
| Assay | ≥97.0% (GC) |
| Grade | purum |
| Melting point | 82-85 °C(lit.)82-85 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)phenylacetic acid used for?
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It is primarily used as a building block in organic synthesis, especially for creating pharmaceutical intermediates and in agrochemical development.
What is the CAS number and chemical formula?
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The CAS number is 32857-62-8 and the chemical formula is CF3C6H4CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a 'purum' grade with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with this chemical?
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This compound is classified with GHS07 and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended PPE includes a dust mask type N95 (US), eyeshields, and gloves.
How is this chemical packed and shipped?
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We ensure secure and compliant packaging for domestic and international shipments, adhering to all relevant transport regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number.
Is this chemical a controlled substance?
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The provided data does not indicate that 4-(Trifluoromethyl)phenylacetic acid is a controlled substance.
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