4-Methylmorpholine
4-Methylmorpholine (CAS: 109-02-4, Formula: C5H11NO) is a versatile heterocyclic organic compound with a molecular weight of 101.15 g/mol. It functions as a critical building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its properties make it suitable for specific applications, including protein sequencing, where high purity is essential.
- IUPAC
- NMM

Chemical Synthesis Intermediate
4-Methylmorpholine serves as a valuable intermediate and building block in organic synthesis, contributing to the construction of more complex molecules, especially within heterocyclic chemistry.
Protein Sequencing
This compound's purity and chemical characteristics make it suitable for applications in protein sequencing methodologies, aiding in the analysis of amino acid sequences.
Reagent in Organic Reactions
As a morpholine derivative, it can be employed as a reagent or catalyst in various organic transformations, leveraging its amine functionality.
| Molecular weight | 101.15 |
|---|---|
| Empirical formula | C5H11NO |
| Assay | 99% |
| Boiling point | 115-116 °C/750 mmHg(lit.) |
| Density | 0.92 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.435(lit.) |
| Vapour pressure | 18 mmHg (20 °C) |
| Melting point | −66 °C(lit.) |
| Vapour density | >1 (vs air) |
| Impurities tested | with OPA-reagent reacting impuritites, none detected (fluorimetric) |
| Suitability | suitable for protein sequencing |



Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 14 °C / 57.2 °F |
| Transport (UN / ADR) | UN 2535 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNa: ≤50 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Absorption | absorption/290 nm cut-off |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylmorpholine used for?
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4-Methylmorpholine is primarily used as a building block in chemical synthesis, particularly in heterocyclic chemistry, and is suitable for applications such as protein sequencing.
What are the CAS number and formula for 4-Methylmorpholine?
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The CAS number for 4-Methylmorpholine is 109-02-4, and its molecular formula is C5H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylmorpholine with an assay of 99%. This product is not represented as USP, BP, or EP grade.
How should 4-Methylmorpholine be handled safely?
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4-Methylmorpholine is a flammable liquid and corrosive. It poses significant hazards including severe skin burns and eye damage, and is harmful if swallowed. Handle with appropriate personal protective equipment, including gloves, goggles, face shields, and respiratory protection, in a well-ventilated area, and keep away from ignition sources.
How is 4-Methylmorpholine packed, shipped, and exported?
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4-Methylmorpholine is packed and shipped according to stringent international regulations for hazardous materials, including UN 2535, Class 8 (3), Packing Group II. TSS is experienced in global export.
How can I request a quote or sample for 4-Methylmorpholine?
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To request a quote or a sample of 4-Methylmorpholine, please contact our sales team through our website or by phone. Specify your quantity requirements for prompt assistance.
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