2′-Aminoacetophenone hydrochloride
2′-Aminoacetophenone hydrochloride (CAS: 25384-14-9) is a chemical compound with the formula C8H9NO · HCl. It serves as a valuable building block in organic synthesis, particularly in the creation of complex heterocyclic structures and other organic molecules. This compound is characterised by its ketone and amine functional groups, making it reactive in various chemical transformations. It is primarily utilised in research and development settings for the synthesis of new chemical entities.

Synthesis of α-Benzamidoacetophenone
2′-Aminoacetophenone hydrochloride has been employed as a precursor in the synthesis of α-benzamidoacetophenone, a compound that may find applications in further chemical research.
Indazole Synthesis
This chemical intermediate is a reported starting material for the synthesis of indazole derivatives. Indazoles are a class of heterocyclic compounds with diverse biological activities, making them targets in medicinal chemistry.
Organic Building Block
As a versatile organic building block, 2′-Aminoacetophenone hydrochloride can be used in various chemical synthesis pathways for the construction of more complex organic molecules. Its functional groups allow for diverse chemical reactions.
| Molecular weight | 171.62 |
|---|---|
| Linear formula | CH3COC6H4NH2 · HCl |
| Assay | 95% |
| Application | 2′-Aminoacetophenone hydrochloride was used in the synthesis of α-benzamidoacetophenone1 and indazoles2. |
| Melting point | 285-289 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Aminoacetophenone hydrochloride used for?
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2′-Aminoacetophenone hydrochloride is used as a building block in organic synthesis, including the preparation of α-benzamidoacetophenone and indazoles.
What are the CAS number and molecular formula for 2′-Aminoacetophenone hydrochloride?
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The CAS number is 25384-14-9, and the molecular formula is C8H9NO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Aminoacetophenone hydrochloride with a minimum assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 2′-Aminoacetophenone hydrochloride be handled?
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Handle 2′-Aminoacetophenone hydrochloride with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust. This compound is classified as causing skin irritation, serious eye irritation, and respiratory irritation.
Is 2′-Aminoacetophenone hydrochloride a controlled substance?
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The provided data does not indicate that 2′-Aminoacetophenone hydrochloride is a controlled substance.
How is 2′-Aminoacetophenone hydrochloride packed, shipped, and exported?
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Tech Serve Solutions packages, ships, and exports chemicals in compliance with all relevant regulations to ensure safe and secure delivery worldwide. Specific packaging details are available upon request.
How can I request a sample or quote for 2′-Aminoacetophenone hydrochloride?
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To request a sample or a quotation for 2′-Aminoacetophenone hydrochloride, please contact our sales team through the TSS website or by phone.
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