2′-Azido-2′-deoxyuridine
2′-Azido-2′-deoxyuridine (CAS: 26929-65-7), with the chemical formula C9H11N5O5 and a molecular weight of 269.21 g/mol, is a modified nucleoside analog. It functions as a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR) upon phosphorylation. This compound is also utilised as a sensitive multi-spectroscopic probe for nucleic acids, offering valuable applications in chemical biology and research.
- IUPAC
- N3-dU
Nucleic Acid Probes
2′-Azido-2′-deoxyuridine serves as a sensitive multi-spectroscopic probe for nucleic acids, enabling advanced research in molecular biology and diagnostics.
Enzyme Inhibition Studies
Upon phosphorylation to N3dUDP, it acts as a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR), making it a valuable tool for studying enzyme mechanisms.
Chemical Biology Research
This azido-modified nucleoside analog is employed in various chemical biology research areas, particularly in studies involving nucleic acid interactions and modifications.
Organic Synthesis Intermediate
As a nucleoside derivative containing an azide group, it can be utilised as a building block in organic synthesis for creating more complex molecules.
| Molecular weight | 269.21 |
|---|---|
| Empirical formula | C9H11N5O5 |
| Assay | ≥98.0% (N) |
| Storage temperature | 2-8°C |
| Application | 2′-Azido-2′-deoxyuridine (N3-dU) upon phosphorylation to 2′-azido-2′-deoxyuridine 5′-diphosphate (N3dUDP) becomes a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR). N3-dU has recently been evaluated for its potential use as a sensitive multi-spectroscopic probe for nucleic acids |
| Melting point | 149-153 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Azido-2′-deoxyuridine used for?
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2′-Azido-2′-deoxyuridine (N3-dU) is used as a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR) upon phosphorylation and as a sensitive multi-spectroscopic probe for nucleic acids in research settings.
What are the CAS number and formula for 2′-Azido-2′-deoxyuridine?
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The CAS number for 2′-Azido-2′-deoxyuridine is 26929-65-7, and its empirical formula is C9H11N5O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Azido-2′-deoxyuridine with a purity of ≥98.0% (N). We do not represent this product as USP, BP, or EP grade.
How should 2′-Azido-2′-deoxyuridine be handled and stored?
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Handle 2′-Azido-2′-deoxyuridine with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the product refrigerated at 2-8°C.
Is 2′-Azido-2′-deoxyuridine a controlled substance?
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The provided data does not indicate that 2′-Azido-2′-deoxyuridine is a controlled substance.
How is 2′-Azido-2′-deoxyuridine packed, shipped, and exported?
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Tech Serve Solutions securely packs and professionally exports fine chemicals like 2′-Azido-2′-deoxyuridine globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2′-Azido-2′-deoxyuridine?
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To request a sample or obtain a quote for 2′-Azido-2′-deoxyuridine, please contact our sales team via the website or direct email.
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