Antalarmin hydrochloride
Antalarmin hydrochloride (CAS 220953-69-5), with the molecular formula C24H34N4·HCl and a molecular weight of 415.01 g/mol, is a non-peptide antagonist of the CRF1 corticotropin-releasing factor receptor. This off-white solid compound is primarily utilised in research settings. Its solubility in DMSO and storage requirements at 2-8°C highlight its nature as a specialised chemical for scientific investigation, particularly in cell biology and neuroscience research.
- IUPAC
- N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolol[2,3-d]pyrimidin-4-amine hydrochloride

Research Chemical
Antalarmin hydrochloride serves as a crucial research tool for investigating the role of corticotropin-releasing factor (CRF) receptors in biological systems. Its specific antagonist activity allows for detailed studies in cell signalling and neuroscience.
Cell Biology Studies
This compound is applied in cell biology research to understand cellular responses mediated by CRF receptors. Its use can help elucidate pathways involved in stress, anxiety, and other physiological processes regulated by the CRF system.
Drug Discovery and Development
As a potential therapeutic candidate targeting CRF1 receptors, Antalarmin hydrochloride is of interest in drug discovery programs. Researchers utilise it to explore novel therapeutic strategies for conditions associated with CRF pathway dysregulation.
| Molecular weight | 415.01 |
|---|---|
| Empirical formula | C24H34N4·HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |
| Application | Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Antalarmin hydrochloride used for?
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Antalarmin hydrochloride is primarily used as a non-peptide CRF1 corticotropin-releasing factor receptor antagonist in research settings, particularly for studies in cell biology, cell signalling, and neuroscience.
What is the CAS number and chemical formula for Antalarmin hydrochloride?
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The CAS number for Antalarmin hydrochloride is 220953-69-5, and its chemical formula is C24H34N4·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Antalarmin hydrochloride with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade unless explicitly stated.
How should Antalarmin hydrochloride be handled and stored?
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Antalarmin hydrochloride is a solid compound that should be stored desiccated at 2-8°C. When handling, it is essential to use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, and to observe a WGK Germany rating of 3.
Is Antalarmin hydrochloride a controlled substance?
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The provided data does not indicate that Antalarmin hydrochloride is a controlled substance.
How is Antalarmin hydrochloride shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Antalarmin hydrochloride, and adheres to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote for Antalarmin hydrochloride?
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To request a sample or quote for Antalarmin hydrochloride, please contact our sales team through the TSS website or via direct inquiry, providing your contact details and specific requirements.
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