4-Methylmorpholine N-oxide
4-Methylmorpholine N-oxide (CAS: 7529-22-8; Formula: C5H11NO2; MW: 117.15 g/mol) is a versatile chemical compound. It functions as a non-metallic catalyst in the cyanosilylation of ketones and as a co-oxidant in asymmetric dihydroxylation reactions. Supplied by Tech Serve Solutions, this reagent is primarily utilised in chemical synthesis and research applications.
- IUPAC
- NMO

Catalyst for Cyanosilylation
4-Methylmorpholine N-oxide serves as an effective non-metallic catalyst for the cyanosilylation of ketones, a key transformation in organic synthesis.
Co-Oxidant in Dihydroxylation
This compound acts as a co-oxidant, notably in the Sharpless asymmetric dihydroxylation process when conducted in ionic liquids, facilitating stereoselective synthesis.
Synthetic Reagent
As a broad synthetic reagent, it finds application in various organic transformations requiring an oxidizing agent or specific catalytic properties.
| Molecular weight | 117.15 |
|---|---|
| Empirical formula | C5H11NO2 |
| Assay | 97% |
| Refractive index | n20/D 1.43 |
| Concentration | ~50% in H2O |
| Storage temperature | 2-8°C |
| Application | Non-metallic catalyst for the cyanosilylation of ketones.1 Co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.2 |
| Melting point | 180-184 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylmorpholine N-oxide primarily used for?
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It is used as a non-metallic catalyst for the cyanosilylation of ketones and as a co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.
What is the CAS number and chemical formula for 4-Methylmorpholine N-oxide?
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The CAS number is 7529-22-8 and the chemical formula is C5H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylmorpholine N-oxide with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-Methylmorpholine N-oxide be handled safely?
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4-Methylmorpholine N-oxide is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle in a well-ventilated area, avoid breathing dust/fume/gas/mist/vapours/spray, and wear protective gloves/eye protection/face protection. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do.
How is 4-Methylmorpholine N-oxide typically supplied and shipped?
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It is typically supplied as a solution of approximately 50% in water and should be stored at 2-8°C. TSS exports globally.
How can I request a quote or sample?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team via our website or by phone, referencing the product name and CAS number 7529-22-8.
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