4-Hydroxyestrone
4-Hydroxyestrone (CAS 3131-23-5), with the molecular formula C18H22O3, is a steroid hormone belonging to the estrogen class. This compound is primarily utilised in biochemical research, particularly in studies related to cell biology, cell signalling, and hormonal pathways. Its structure allows it to interact with estrogen receptors, making it a valuable tool for investigating endocrine functions and related physiological processes in vitro. It is supplied by TSS with an assay of ≥90% (HPLC) and stored at −20°C.
- IUPAC
- 1,3,5(10)-Estratriene-3,4-diol-17-one
Research in Endocrinology
4-Hydroxyestrone serves as a key compound in endocrinology research, enabling the study of estrogenic effects and mechanisms. Its use facilitates investigations into hormone-receptor interactions and downstream signalling pathways relevant to reproductive health and other physiological processes.
Cell Biology Studies
In cell biology, 4-Hydroxyestrone is employed to examine cellular responses to hormonal stimuli. Researchers use it to probe the impact of estrogens on cell growth, differentiation, and gene expression within various biological models.
Neuroscience Research
This compound finds application in neuroscience for investigating the role of estrogens in the central nervous system. Studies may explore its influence on neuronal function, neuroprotection, and cognitive processes.
Biochemical Assays
4-Hydroxyestrone is utilised as a standard or substrate in various biochemical assays, particularly those focused on enzyme activity or receptor binding studies within the steroid hormone research field.
| Molecular weight | 286.37 |
|---|---|
| Empirical formula | C18H22O3 |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxyestrone used for?
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4-Hydroxyestrone is used in research for studies in endocrinology, cell biology, neuroscience, and biochemical assays, particularly those investigating estrogenic effects and hormonal pathways.
What are the CAS number and chemical formula for 4-Hydroxyestrone?
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The CAS number for 4-Hydroxyestrone is 3131-23-5, and its empirical formula is C18H22O3.
What grade and purity does Tech Serve Solutions supply for 4-Hydroxyestrone?
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Tech Serve Solutions supplies 4-Hydroxyestrone with an assay of ≥90% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should 4-Hydroxyestrone be handled and stored?
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4-Hydroxyestrone should be stored at −20°C. When handling, it is recommended to use safety measures including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, as indicated by its safety data. The flash point is 93°C (199.4°F), indicating it is combustible.
Is 4-Hydroxyestrone a controlled substance?
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The provided data does not indicate that 4-Hydroxyestrone is a controlled substance.
How is 4-Hydroxyestrone packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details are available upon request for 4-Hydroxyestrone.
How can I request a quote or sample for 4-Hydroxyestrone?
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To request a quote or sample for 4-Hydroxyestrone, please contact the Tech Serve Solutions sales team through our official channels.
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