4-Hydroxytolbutamide
4-Hydroxytolbutamide (CAS 5719-85-7) is a chemical compound with the molecular formula C12H18N2O4S and a molecular weight of 286.35 g/mol. This white solid serves as a valuable reference standard in biochemical and pharmacological research. Its primary application involves its use in assays for studying the biotransformation of related compounds, particularly in the field of drug metabolism and xenobiotic studies.
- IUPAC
- N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide
Reference Standard in Biotransformation Assays
4-Hydroxytolbutamide is utilised as a standard for accurately quantifying the fungal biotransformation of tolbutamide to its 4'-hydroxy metabolite. This application is crucial in drug metabolism studies and understanding xenobiotic pathways.
Research in Drug Metabolism
This compound is employed in research focused on drug metabolism and xenobiotic interactions. It aids in the characterisation of metabolic pathways and enzyme activities involved in drug processing within biological systems.
Cell Biology and Signaling Research
As a bioactive small molecule, 4-Hydroxytolbutamide may find applications in cell biology research, particularly in studies related to cell signaling pathways and neuroscience, given its structural class.
| Molecular weight | 286.35 |
|---|---|
| Empirical formula | C12H18N2O4S |
| Assay | ≥98% (HPLC) |
| Colour | white |
| Solubility | ethanol: soluble12 mg/mL0.1 M NaOH: soluble4 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | 4-Hydroxytolbutamide has been used as a standard to assay the fungal biotransformation of tolbutamide to 4′-hydroxytolbutamide1. |
| Melting point | 100-102 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxytolbutamide used for?
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4-Hydroxytolbutamide is primarily used as a reference standard in assays to study the biotransformation of tolbutamide to 4′-hydroxytolbutamide, particularly in fungal metabolism research and drug metabolism studies.
What is the CAS number and chemical formula for 4-Hydroxytolbutamide?
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The CAS number is 5719-85-7 and the empirical formula (in Hill notation) is C12H18N2O4S.
What grade and purity does Tech Serve Solutions supply for 4-Hydroxytolbutamide?
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Tech Serve Solutions supplies 4-Hydroxytolbutamide with an assay of ≥98% (HPLC). This is a research-grade chemical and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should 4-Hydroxytolbutamide be handled and stored?
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Handle 4-Hydroxytolbutamide with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It should be stored at 2-8°C.
Is 4-Hydroxytolbutamide a controlled substance?
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The provided data does not indicate that 4-Hydroxytolbutamide is a controlled substance. WGK Germany is 3, indicating a high hazard.
How can I request a quote or sample for 4-Hydroxytolbutamide?
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To request a quote or sample of 4-Hydroxytolbutamide, please contact the Tech Serve Solutions sales department through our website or by phone.
How is 4-Hydroxytolbutamide exported and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. 4-Hydroxytolbutamide is carefully packaged and shipped according to international regulations for chemical transport.
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