4-Hydroxyestradiol

CAS 5976-61-4C18H24O3Cell Biology

4-Hydroxyestradiol (CAS: 5976-61-4), with the molecular formula C18H24O3 and a molecular weight of 288.38 g/mol, is a steroidal compound. It is a key metabolite of estradiol and plays a role in oestrogen metabolism and signalling pathways. Primarily utilised in biochemical research and cell biology studies, it serves as a valuable tool for investigating hormonal effects and related biological processes.

IUPAC: 1,3,5(10)-Estratriene-3,4,17β-triol

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4-Hydroxyestradiol (C18H24O3) — chemical structure, CAS 5976-61-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell Biology

01 /Applications

Biochemical Research

4-Hydroxyestradiol is employed in laboratory settings for studying oestrogen metabolism, receptor binding, and cellular responses to hormonal stimuli. Its use supports fundamental research in endocrinology and molecular biology.

Cell Biology Studies

As a bioactive small molecule, it aids in investigating cell proliferation, differentiation, and other cellular functions influenced by oestrogenic pathways. Researchers utilise it to understand the mechanisms of hormone action at the cellular level.

Endocrinology Research

This compound is valuable for exploring the complex interactions within the endocrine system. It helps elucidate the roles of various oestrogen metabolites in physiological and pathological processes.

02 /Properties

Molecular weight	288.38
Empirical formula	C18H24O3
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P281Use personal protective equipment as required

Protective equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	40
Safety statements (S)	22-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5976-61-4

MDL number

MFCD00063335

PubChem substance

24895648

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Hydroxyestradiol used for?

4-Hydroxyestradiol is primarily used in biochemical research and cell biology studies to investigate oestrogen metabolism and signalling pathways.

What are the CAS number and formula for 4-Hydroxyestradiol?

The CAS number for 4-Hydroxyestradiol is 5976-61-4, and its molecular formula is C18H24O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-Hydroxyestradiol as a research chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.

How should 4-Hydroxyestradiol be handled and stored?

4-Hydroxyestradiol requires careful handling due to potential health hazards (H351). It should be stored at -20°C. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3), must be used.

Is 4-Hydroxyestradiol a controlled substance?

The provided data does not indicate that 4-Hydroxyestradiol is a scheduled or controlled substance.

How is 4-Hydroxyestradiol packed and shipped?

4-Hydroxyestradiol is packed and exported according to standard chemical shipping regulations. Please contact TSS for specific details regarding packaging and international export.