3-Amino-5-(trifluoromethyl)benzoic acid
3-Amino-5-(trifluoromethyl)benzoic acid (CAS: 328-68-7; C8H6F3NO2) is a trifluoromethyl-substituted aromatic amino acid. With a molecular weight of 205.13 g/mol, this compound serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and the development of novel chemical entities, particularly within the fields of chemical biology and peptide chemistry, owing to its unique structural features.

Chemical Synthesis Intermediate
This compound is employed as a key intermediate in the synthesis of more complex organic molecules. Its trifluoromethyl and amino groups offer distinct reactive sites for various chemical transformations.
Peptide Chemistry
Utilised in the construction of modified peptides. The incorporation of unnatural amino acid derivatives like this one can confer unique properties to peptide structures.
Chemical Biology Research
Serves as a reagent or building block in studies exploring biological pathways and molecular interactions. Its fluorinated nature can aid in biophysical studies.
Development of Novel Compounds
A foundational component for creating new chemical entities with potential applications in pharmaceuticals and material science. Its structure is valuable for medicinal chemistry efforts.
| Molecular weight | 205.13 |
|---|---|
| Empirical formula | C8H6F3NO2 |
| Assay | 97% |
| Melting point | 141-146 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Amino-5-(trifluoromethyl)benzoic acid used for?
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3-Amino-5-(trifluoromethyl)benzoic acid is primarily used as an intermediate in chemical synthesis, particularly in peptide chemistry and chemical biology research for the development of novel compounds.
What are the CAS number and chemical formula for 3-Amino-5-(trifluoromethyl)benzoic acid?
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The CAS number for 3-Amino-5-(trifluoromethyl)benzoic acid is 328-68-7, and its chemical formula is C8H6F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Amino-5-(trifluoromethyl)benzoic acid with an assay of 97%. This product is not guaranteed to be USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for 3-Amino-5-(trifluoromethyl)benzoic acid?
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3-Amino-5-(trifluoromethyl)benzoic acid is classified under GHS07 with a Warning signal word. It is labelled with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
Is 3-Amino-5-(trifluoromethyl)benzoic acid a controlled substance?
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Based on the provided data, 3-Amino-5-(trifluoromethyl)benzoic acid is not listed as a controlled substance.
How is 3-Amino-5-(trifluoromethyl)benzoic acid packed and shipped globally?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, adhering to international shipping regulations for safe and secure transportation.
How can I request a quote or sample for 3-Amino-5-(trifluoromethyl)benzoic acid?
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Please contact our sales department through our website or by phone to request a quotation or to arrange for a sample of 3-Amino-5-(trifluoromethyl)benzoic acid.
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