4-Hydroxy-TEMPO benzoate
4-Hydroxy-TEMPO benzoate (CAS 3225-26-1), with the molecular formula C16H22NO3, is a stable nitroxide radical derivative. It serves as a versatile reagent in organic synthesis, particularly in oxidation reactions and as a radical mediator. Its unique structure enables controlled radical processes, making it valuable in research and development within chemical and materials science sectors. Tech Serve Solutions supplies this compound for laboratory and industrial applications.
- IUPAC
- 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl benzoate

Oxidation Catalyst
Utilised as a catalyst or co-catalyst in selective oxidation of alcohols to aldehydes or ketones. Its radical nature allows for efficient and controlled oxidation pathways.
Radical Polymerisation Mediator
Employed in nitroxide-mediated polymerisation (NMP) to control polymer chain growth, leading to polymers with defined architectures and molecular weights.
Spin Labeling Studies
Its paramagnetic nature makes it suitable for Electron Paramagnetic Resonance (EPR) spectroscopy, aiding in studies of molecular dynamics and structures.
Synthetic Reagent
A key reagent in various organic transformations requiring a stable radical source or a mediator for selective reactions.
| Molecular weight | 276.35 |
|---|---|
| Empirical formula | C16H22NO3 |
| Assay | ≥97.0% (CHN) |
| Melting point | 99-101 °C(lit.)99-106 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-TEMPO benzoate used for?
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4-Hydroxy-TEMPO benzoate is used as a catalyst or mediator in selective oxidation reactions and in controlled radical polymerisation processes like NMP. It also finds application in spin labeling studies via EPR spectroscopy.
What is the CAS number and molecular formula for 4-Hydroxy-TEMPO benzoate?
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The CAS number is 3225-26-1 and the molecular formula is C16H22NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-TEMPO benzoate with an assay of ≥97.0% (CHN). This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or any pharmacopoeia grade.
How should 4-Hydroxy-TEMPO benzoate be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a high hazard to water.
Is 4-Hydroxy-TEMPO benzoate a controlled substance?
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The provided data does not indicate that 4-Hydroxy-TEMPO benzoate is a controlled substance.
How is 4-Hydroxy-TEMPO benzoate packed and shipped?
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4-Hydroxy-TEMPO benzoate is packed and shipped according to standard chemical handling and international shipping regulations to ensure safe transit.
How can I request a sample or quote for 4-Hydroxy-TEMPO benzoate?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our official website or contact details provided.
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