4-Hydroxybenzamide
4-Hydroxybenzamide (CAS 619-57-8), with a molecular formula of HOC₆H₄CONH₂ and a molecular weight of 137.14 g/mol, is a valuable organic compound. As a benzamide derivative featuring a hydroxyl group, it serves as a key building block in chemical synthesis. Its applications are primarily focused on the preparation of more complex molecules, notably in pharmaceutical research and development for novel therapeutic agents.
Synthesis of Pharmaceutical Intermediates
4-Hydroxybenzamide functions as a crucial intermediate in the synthesis of complex organic molecules. It has been notably utilised in the preparation of balanol, a potent inhibitor of protein kinase C (PKC).
Organic Synthesis Building Block
This compound is a versatile building block in organic chemistry. Its functional groups (amide and phenol) allow for diverse chemical transformations, facilitating the construction of various molecular architectures.
Research and Development
In R&D settings, 4-Hydroxybenzamide is employed for exploring new synthetic pathways and developing novel compounds with potential biological activities. Its defined structure makes it reliable for targeted synthesis projects.
| Molecular weight | 137.14 |
|---|---|
| Linear formula | HOC6H4CONH2 |
| Assay | 98% |
| Application | 4-Hydroxybenzamide was used in the synthesis of balanol, a potent protein kinase C (PKC) inhibitor1. |
| Melting point | 161-162 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxybenzamide used for?
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4-Hydroxybenzamide is used as a building block in chemical synthesis, particularly in the preparation of pharmaceutical intermediates, such as balanol, a protein kinase C inhibitor.
What are the CAS number and formula for 4-Hydroxybenzamide?
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The CAS number for 4-Hydroxybenzamide is 619-57-8, and its linear formula is HOC₆H₄CONH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxybenzamide with an assay of 98%. This is typically a research or technical grade, and we do not represent it as USP, BP, or EP grade.
How should 4-Hydroxybenzamide be handled safely?
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4-Hydroxybenzamide is classified with warning signal words and hazard statements including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Safe handling requires wearing a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is 4-Hydroxybenzamide a controlled substance?
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Based on the provided data, 4-Hydroxybenzamide is not indicated as a controlled substance.
How is 4-Hydroxybenzamide packed, shipped, and exported?
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Tech Serve Solutions handles packing and shipping according to industry best practices and international regulations for chemical export. Specific details will be provided upon order confirmation.
How can I request a sample or quote for 4-Hydroxybenzamide?
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To request a sample or quote for 4-Hydroxybenzamide, please contact our sales department via the website or by phone, providing your specific requirements.
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