4-Fluoro-2-methylbenzenesulfonyl chloride
4-Fluoro-2-methylbenzenesulfonyl chloride (CAS: 7079-48-3; Formula: FC6H3(CH3)SO2Cl; MW: 208.64) is a fluorinated organic building block. It serves as a key intermediate in organic synthesis, particularly for introducing the 4-fluoro-2-methylbenzenesulfonyl group into target molecules. This compound is valuable in the development of pharmaceuticals, agrochemicals, and specialty materials requiring specific electronic or steric properties imparted by its unique structure. Tech Serve Solutions supplies this chemical for research and industrial applications.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where the fluorinated sulfonyl moiety is a critical structural component for biological activity. Its structure can influence lipophilicity and binding interactions.
Agrochemical Development
Serves as a building block for novel pesticides and herbicides. The presence of fluorine can enhance efficacy and metabolic stability in agrochemical formulations.
Organic Synthesis Reagent
A versatile reagent for sulfonylation reactions, enabling the introduction of the 4-fluoro-2-methylbenzenesulfonyl group onto various nucleophiles. It is useful in creating complex organic molecules.
Materials Science
Incorporated into polymers or functional materials to modify properties such as thermal stability, dielectric constant, or surface energy due to the presence of the fluorine atom and sulfonyl group.
| Molecular weight | 208.64 |
|---|---|
| Linear formula | FC6H3(CH3)SO2Cl |
| Assay | 97% |
| Boiling point | 245-246 °C(lit.) |
| Density | 1.433 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5370 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-methylbenzenesulfonyl chloride used for?
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4-Fluoro-2-methylbenzenesulfonyl chloride is primarily used as a building block in organic synthesis for pharmaceuticals, agrochemicals, and materials science applications, enabling the introduction of the 4-fluoro-2-methylbenzenesulfonyl group.
What are the CAS number and chemical formula for 4-Fluoro-2-methylbenzenesulfonyl chloride?
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The CAS number is 7079-48-3 and the chemical formula is FC6H3(CH3)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-methylbenzenesulfonyl chloride with an assay of 97%. This is a technical or research grade, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Fluoro-2-methylbenzenesulfonyl chloride be handled?
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Handle with extreme caution. This compound is corrosive and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, face shields, and respiratory protection (type ABEK or equivalent), is essential. Ensure adequate ventilation.
Is 4-Fluoro-2-methylbenzenesulfonyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can ship 4-Fluoro-2-methylbenzenesulfonyl chloride internationally, adhering to all transport regulations (UN 3265, Class 8, PG II).
How can I request a quote or sample for 4-Fluoro-2-methylbenzenesulfonyl chloride?
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To request a quote or sample, please contact the TSS sales department via the website or by phone, providing your specific requirements and shipping details.
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