4-Chloro-2-fluoro-5-nitrotoluene
4-Chloro-2-fluoro-5-nitrotoluene (CAS: 18349-11-6), with the molecular formula ClC6H2(F)(NO2)CH3 and a molecular weight of 189.57 g/mol, is a fluorinated organic building block. This compound serves as a valuable intermediate in chemical synthesis, particularly within the fields of pharmaceuticals and agrochemicals, owing to its specific arrangement of functional groups that allow for further chemical transformations.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure, featuring chloro, fluoro, and nitro substituents on a toluene backbone, offers synthetic chemists a versatile platform for drug discovery and development.
Agrochemical Synthesis
Serves as a key building block in the creation of novel agrochemicals, including pesticides and herbicides. The presence of fluorine often enhances the biological activity and metabolic stability of the final products.
Organic Synthesis Reagent
A versatile reagent for introducing specific chemical functionalities into organic molecules. Its reactivity profile makes it suitable for various coupling reactions and derivatisations in complex molecule construction.
| Molecular weight | 189.57 |
|---|---|
| Linear formula | ClC6H2(F)(NO2)CH3 |
| Assay | 98% |
| Melting point | 42-45 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-fluoro-5-nitrotoluene used for?
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4-Chloro-2-fluoro-5-nitrotoluene is primarily used as an intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 4-Chloro-2-fluoro-5-nitrotoluene?
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The CAS number is 18349-11-6, and the molecular formula is ClC6H2(F)(NO2)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2-fluoro-5-nitrotoluene with an assay of 98%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP.
How should 4-Chloro-2-fluoro-5-nitrotoluene be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 4-Chloro-2-fluoro-5-nitrotoluene available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Chloro-2-fluoro-5-nitrotoluene, adhering to international shipping regulations.
How can I request a sample or quote for 4-Chloro-2-fluoro-5-nitrotoluene?
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To request a sample or quote, please contact our sales department through the website or by phone, providing your contact details and the desired quantity.
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