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4-Chloro-2-fluoroaniline

CAS 57946-56-2ClC6H3(F)NH2Chemical Synthesis

4-Chloro-2-fluoroaniline (CAS 57946-56-2), with the molecular formula ClC6H3(F)NH2 and a molecular weight of 145.56 g/mol, is a halogenated aromatic amine. This compound serves as a valuable building block in organic synthesis. Its utility lies primarily in the creation of more complex molecules, particularly within the pharmaceutical and agrochemical industries, due to the presence of both fluorine and chlorine substituents on the aniline ring.

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4-Chloro-2-fluoroaniline (ClC6H3(F)NH2) — chemical structure, CAS 57946-56-2; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisFluorinated Building BlocksNitrogen CompoundsOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

4-Chloro-2-fluoroaniline is employed as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the introduction of specific functionalities crucial for drug discovery and development.

Agrochemical Synthesis

This chemical is utilised in the production of active ingredients for agrochemicals. The fluorinated and chlorinated aromatic moiety can impart desirable properties to pesticides and herbicides.

Organic Synthesis Building Block

As a versatile building block, 4-Chloro-2-fluoroaniline is frequently used in academic and industrial research for constructing novel organic molecules. It is particularly useful for introducing halogenated aniline fragments into target structures.

02 /Properties
Molecular weight145.56
Linear formulaClC6H3(F)NH2
Assay98%
Density1.311 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.56(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point99 °C / 210.2 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22-36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
57946-56-2
MDL number
MFCD00010625
PubChem substance
24859065
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chloro-2-fluoroaniline used for?

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4-Chloro-2-fluoroaniline is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. Its specific structure makes it valuable for introducing fluorinated and chlorinated aniline fragments into target molecules.

What is the CAS number and formula for 4-Chloro-2-fluoroaniline?

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The CAS number for 4-Chloro-2-fluoroaniline is 57946-56-2, and its molecular formula is ClC6H3(F)NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Chloro-2-fluoroaniline with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 4-Chloro-2-fluoroaniline be handled?

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4-Chloro-2-fluoroaniline is a Warning substance and is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including safety glasses, face shield, gloves, and a suitable respirator, should be used. Handle in a well-ventilated area.

Is 4-Chloro-2-fluoroaniline a controlled substance?

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The provided data does not indicate that 4-Chloro-2-fluoroaniline is a controlled substance.

How is 4-Chloro-2-fluoroaniline packed and shipped?

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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations. Packing details are available upon request.

How can I request a quote or sample?

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To request a quote or sample of 4-Chloro-2-fluoroaniline, please contact our sales team through the website or by phone.

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