4-Bromo-3-fluorobenzenesulfonyl chloride
4-Bromo-3-fluorobenzenesulfonyl chloride (CAS: 351003-51-5), with the molecular formula BrC6H3(F)SO2Cl and a molecular weight of 273.51 g/mol, is a key organic intermediate. It serves as a versatile building block in chemical synthesis, particularly in the development of novel fluorinated organic compounds. Its sulfonyl chloride functionality makes it reactive for derivatization in pharmaceutical and agrochemical research.

Organic Synthesis Intermediate
This compound acts as a crucial intermediate in the synthesis of more complex organic molecules. The presence of bromine, fluorine, and the sulfonyl chloride group allows for diverse chemical transformations.
Pharmaceutical Research
It is employed as a building block in the discovery and development of new pharmaceutical agents, leveraging its unique halogenated aromatic structure.
Agrochemical Development
The compound finds application in the synthesis of active ingredients for agrochemicals, contributing to the development of crop protection solutions.
Material Science
As a fluorinated organic compound, it may be utilised in the design and synthesis of specialized materials with unique properties.
| Molecular weight | 273.51 |
|---|---|
| Linear formula | BrC6H3(F)SO2Cl |
| Assay | 97% |
| Density | 1.850 g/mL at 25 °C(lit.) |
| Refractive index | n20/D >1.5770(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-3-fluorobenzenesulfonyl chloride used for?
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4-Bromo-3-fluorobenzenesulfonyl chloride (CAS: 351003-51-5) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and molecular formula for 4-Bromo-3-fluorobenzenesulfonyl chloride?
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The CAS number is 351003-51-5 and the molecular formula is BrC6H3(F)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-3-fluorobenzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-Bromo-3-fluorobenzenesulfonyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, face shields, and suitable respiratory protection, must be used. Handle only in well-ventilated areas.
How is 4-Bromo-3-fluorobenzenesulfonyl chloride packed and shipped?
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This chemical is shipped as a hazardous material (UN 3265, Class 8, Packing Group II) in compliance with international regulations for export.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quotation or a sample of 4-Bromo-3-fluorobenzenesulfonyl chloride.
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