4-Bromo-3-fluorophenylzinc iodide solution
4-Bromo-3-fluorophenylzinc iodide solution (CAS 352525-65-6, BrC6H3(F)ZnI) is an organozinc halide reagent with a molecular weight of 366.28 g/mol. Supplied as a 0.5 M solution in THF, it is formulated to facilitate its use in various synthetic organic chemistry applications. This reagent is valuable for introducing the 4-bromo-3-fluorophenyl moiety into organic molecules, particularly in cross-coupling reactions.
Cross-Coupling Reactions
Utilised in palladium- or nickel-catalysed cross-coupling reactions (e.g., Negishi coupling) for the formation of carbon-carbon bonds. It is effective for arylating substrates with the 4-bromo-3-fluorophenyl group.
Organozinc Reagent Synthesis
Serves as a precursor in the synthesis of more complex organozinc compounds or for direct functionalisation of organic molecules.
Pharmaceutical Intermediate Synthesis
Employed in the construction of advanced intermediates for the pharmaceutical industry, enabling the introduction of fluorinated and brominated aromatic systems.
Materials Science
Can be applied in the synthesis of functional organic materials where precise aryl substitution patterns are required.
| Molecular weight | 366.28 |
|---|---|
| Linear formula | BrC6H3(F)ZnI |
| Density | 1.035 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-3-fluorophenylzinc iodide solution used for?
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It is primarily used as a reagent in organic synthesis, particularly for introducing the 4-bromo-3-fluorophenyl group into organic molecules via cross-coupling reactions and for the synthesis of complex organozinc compounds.
What are the CAS number and formula for 4-Bromo-3-fluorophenylzinc iodide solution?
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The CAS number is 352525-65-6 and the chemical formula is BrC6H3(F)ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. Specific purity details beyond its concentration and solvent are not detailed in the available product data. TSS does not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should 4-Bromo-3-fluorophenylzinc iodide solution be handled safely?
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This solution is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources, and store refrigerated at 2-8°C. Always consult the Safety Data Sheet (SDS) before use.
Is 4-Bromo-3-fluorophenylzinc iodide solution a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is this chemical packed and shipped?
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The product is supplied as a 0.5 M solution in THF and is classified under UN 2056, Hazard Class 3, Packing Group II, indicating it is a flammable liquid. It is exported by TSS following all relevant transport regulations.
How can I request a sample or quote for this product?
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Please contact our sales team directly via the website or provide your details to request a quote or sample.
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