4-Bromo-3-fluoroaniline
4-Bromo-3-fluoroaniline (CAS: 656-65-5), with the molecular formula BrC6H3(F)NH2 and a molecular weight of 190.01 g/mol, is a fluorinated organic building block. It serves as a key intermediate in the synthesis of more complex molecules. Utilised primarily in chemical research and development, this compound is valuable for introducing specific halogen and amine functionalities into organic structures, particularly within the pharmaceutical and agrochemical sectors.

Pharmaceutical Intermediate
4-Bromo-3-fluoroaniline is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its unique substitution pattern allows for targeted modifications in drug discovery programmes.
Agrochemical Synthesis
This compound can act as a precursor in the development of novel pesticides and herbicides. The presence of bromine and fluorine can contribute to the biological activity of the final agrochemical product.
Organic Synthesis Building Block
As a versatile building block, it is used in general organic synthesis to create substituted aromatic compounds. Its reactive amine group and halogen substituents offer multiple synthetic pathways.
Materials Science Research
This molecule may find application in the synthesis of specialised polymers or functional materials where specific electronic or physical properties are desired due to its halogenated aromatic structure.
| Molecular weight | 190.01 |
|---|---|
| Linear formula | BrC6H3(F)NH2 |
| Assay | 97% |
| Boiling point | 65-68 °C(lit.) |
| Density | 0.982 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.471(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-3-fluoroaniline used for?
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4-Bromo-3-fluoroaniline is primarily used as an intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals, as well as in materials science research.
What are the CAS number and formula for 4-Bromo-3-fluoroaniline?
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The CAS number for 4-Bromo-3-fluoroaniline is 656-65-5, and its chemical formula is BrC6H3(F)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-3-fluoroaniline with a minimum purity of 97%. This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 4-Bromo-3-fluoroaniline be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust and contact with skin and eyes, as it can cause skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335).
How is 4-Bromo-3-fluoroaniline packed and exported?
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Tech Serve Solutions professionally packs and exports 4-Bromo-3-fluoroaniline globally, adhering to all relevant shipping and safety regulations for chemical substances.
How can I request a sample or quote for 4-Bromo-3-fluoroaniline?
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To request a sample or a quote, please contact our sales department through the website or by calling us directly. Our team will assist you promptly.
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