4-Amino-nicotinic acid
4-Amino-nicotinic acid (CAS 7418-65-7), with the chemical formula C6H6N2O2 and a molecular weight of 138.12 g/mol, is a pyridine derivative. This compound functions as a valuable building block in organic synthesis. It is primarily utilised in the preparation of heterocyclic compounds, such as 2-methyl-pyrido-oxazine, and finds applications in chemical biology and peptide chemistry research.
- IUPAC
- 4-Amino-3-pyridinecarboxylic acid
- Synonyms
- 4-Amino-3-pyridinecarboxylic acid

Organic Synthesis Intermediate
4-Amino-nicotinic acid serves as a key intermediate in the synthesis of various organic molecules. Its structure allows for diverse chemical transformations, making it useful in constructing complex heterocyclic frameworks.
Preparation of Heterocyclic Compounds
This compound has been employed in the preparation of specific heterocyclic systems, notably 2-methyl-pyrido-oxazine. This highlights its utility in designing novel ring structures for research purposes.
Chemical Biology Research
As a pyridine derivative and unnatural amino acid analogue, 4-Amino-nicotinic acid can be utilised in chemical biology to explore biological pathways or develop new probes.
| Molecular weight | 138.12 |
|---|---|
| Empirical formula | C6H6N2O2 |
| Assay | ≥97.0% (HPLC) |
| Impurities tested | ≤1.0% water |
| Application | 4-Aminonicotinic acid has been used in the preparation of 2-methyl-pyrido-oxazine. |
| Melting point | 307-312 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-nicotinic acid used for?
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4-Amino-nicotinic acid is primarily used as a building block in organic synthesis, particularly for the preparation of heterocyclic compounds such as 2-methyl-pyrido-oxazine. It also finds applications in chemical biology and peptide chemistry research.
What are the CAS number and formula for 4-Amino-nicotinic acid?
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The CAS number for 4-Amino-nicotinic acid is 7418-65-7, and its chemical formula is C6H6N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Amino-nicotinic acid with an assay of ≥97.0% (HPLC) and contains ≤1.0% water. This is a research-grade chemical and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Amino-nicotinic acid be handled safely?
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Warning: Causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.
Does TSS export 4-Amino-nicotinic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Amino-nicotinic acid.
How can I request a quote or sample for 4-Amino-nicotinic acid?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our website or by phone, referencing product code 7418-65-7.
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