Hydroxyflutamide
Hydroxyflutamide (CAS: 52806-53-8), with the molecular formula C11H11F3N2O4 and a molecular weight of 292.21 g/mol, is a non-steroidal anti-androgen. It functions by inhibiting the action of androgens. Supplied as a white to tan powder, this compound is primarily utilised in scientific research settings, particularly within cell biology and endocrinology studies, to investigate hormonal pathways and their effects.
- IUPAC
- 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide,2-Hydroxyflutamide,Hydroxyniphtholide,Sch 16423,a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide
- Synonyms
- 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide2-HydroxyflutamideHydroxyniphtholideSch 16423a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide

Androgen Receptor Antagonist Research
Hydroxyflutamide serves as a valuable tool in research for studying the role of androgen receptors in various biological processes. Its ability to block androgen binding allows scientists to probe cellular responses to hormonal signals.
Cell Biology and Signaling Studies
In cell biology, this compound aids in the investigation of cell signaling pathways regulated by androgens. It is used to understand the mechanisms of hormone action at the cellular level, particularly in systems sensitive to androgens.
Drug Candidate and Therapeutics Research
As an approved therapeutic and drug candidate, Hydroxyflutamide is employed in research aiming to develop or understand treatments involving hormonal imbalances. Its mechanism provides a basis for exploring new therapeutic strategies.
| Molecular weight | 292.21 |
|---|---|
| Empirical formula | C11H11F3N2O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | room temp |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxyflutamide used for?
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Hydroxyflutamide is used in scientific research, particularly in cell biology and endocrinology, to study androgen receptor antagonism and related cellular signaling pathways.
What are the CAS number and formula for Hydroxyflutamide?
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The CAS number for Hydroxyflutamide is 52806-53-8, and its empirical formula is C11H11F3N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydroxyflutamide with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety concerns when handling Hydroxyflutamide?
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Hydroxyflutamide is classified with GHS07 symbol and a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is Hydroxyflutamide packed and shipped by TSS?
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Hydroxyflutamide is typically supplied as a powder and stored under desiccated conditions at room temperature. TSS exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample of Hydroxyflutamide?
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To request a quote or a sample of Hydroxyflutamide, please use the contact form on our website or reach out to our sales department directly.
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