Hydroxyurea
Hydroxyurea (CAS: 127-07-1) is a urea derivative with the molecular formula NH2CONHOH and a molecular weight of 76.05 g/mol. This compound is recognised for its role in biological research, particularly within cell biology. It is often employed as a biochemical tool due to its specific mechanisms of action, making it valuable in various laboratory settings for investigating cellular processes.
- IUPAC
- Hydroxycarbamide
- Synonyms
- Hydroxycarbamide
Biochemical Research
Hydroxyurea serves as a crucial reagent in biochemical and cell biology research. Its ability to inhibit DNA synthesis makes it a valuable tool for studying cell cycle progression and DNA replication mechanisms in vitro.
Cell Cycle Studies
Utilised in laboratories to synchronise cell populations or to arrest cells at specific phases of the cell cycle. This allows for more precise analysis of cellular events and responses to various stimuli.
Inhibitor of Ribonucleotide Reductase
It acts as a potent inhibitor of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. This property is extensively exploited in experimental research settings.
| Molecular weight | 76.05 |
|---|---|
| Linear formula | NH2CONHOH |
| Assay | 98% |
| Solubility | H2O: soluble50 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H340May cause genetic defects
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 46-63 |
| Safety statements (S) | 53-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxyurea primarily used for?
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Hydroxyurea (CAS: 127-07-1) is primarily used in biochemical and cell biology research as a tool to study DNA synthesis, cell cycle progression, and as an inhibitor of ribonucleotide reductase.
What is the CAS number and molecular formula for Hydroxyurea?
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The CAS number for Hydroxyurea is 127-07-1, and its molecular formula is NH2CONHOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydroxyurea with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and laboratory use.
How should Hydroxyurea be handled and stored safely?
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Hydroxyurea is classified with danger signal word and carries hazard statements H340 (May cause genetic defects) and H361 (Suspected of damaging fertility or the unborn child). It should be handled with extreme caution in a well-ventilated area, using appropriate personal protective equipment, and stored at 2-8°C. Follow all safety instructions, including P201, P281, and P308 + P313.
How is Hydroxyurea packed and shipped?
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Hydroxyurea is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for Hydroxyurea?
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To request a sample or a quote for Hydroxyurea, please contact the Tech Serve Solutions sales team through our website or by phone.
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